ID   A0A0F9XP14_TRIHA        Unreviewed;       893 AA.
AC   A0A0F9XP14;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=MHD domain-containing protein {ECO:0000259|PROSITE:PS51072};
GN   ORFNames=THAR02_01462 {ECO:0000313|EMBL:KKP06411.1};
OS   Trichoderma harzianum (Hypocrea lixii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX   NCBI_TaxID=5544 {ECO:0000313|EMBL:KKP06411.1, ECO:0000313|Proteomes:UP000034112};
RN   [1] {ECO:0000313|Proteomes:UP000034112}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T6776 {ECO:0000313|Proteomes:UP000034112};
RX   PubMed=26067977; DOI=10.1128/genomeA.00647-15;
RA   Baroncelli R., Piaggeschi G., Fiorini L., Bertolini E., Zapparata A.,
RA   Pe M.E., Sarrocco S., Vannacci G.;
RT   "Draft whole-genome sequence of the biocontrol agent Trichoderma harzianum
RT   T6776.";
RL   Genome Announc. 3:E0064715-E0064715(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKP06411.1}.
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DR   EMBL; JOKZ01000026; KKP06411.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F9XP14; -.
DR   OMA; FQTHEVD; -.
DR   OrthoDB; 2056337at2759; -.
DR   Proteomes; UP000034112; Unassembled WGS sequence.
DR   CDD; cd09264; AP_Syp1_MHD; 1.
DR   CDD; cd07650; F-BAR_Syp1p_like; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001060; FCH_dom.
DR   InterPro; IPR028565; MHD.
DR   InterPro; IPR018808; Muniscin_C.
DR   InterPro; IPR049609; Syp1-like_MHD.
DR   PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR   PANTHER; PTHR23065:SF54; SUPPRESSOR OF YEAST PROFILIN DELETION; 1.
DR   Pfam; PF00611; FCH; 1.
DR   Pfam; PF10291; muHD; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS51072; MHD; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000034112};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          614..872
FT                   /note="MHD"
FT                   /evidence="ECO:0000259|PROSITE:PS51072"
FT   REGION          138..160
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          237..302
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          317..468
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          561..614
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          853..873
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        237..295
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        319..333
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        342..358
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        388..461
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        587..602
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   893 AA;  97555 MW;  48C7578417DEC6CB CRC64;
     MDETPRTEYP AMLAHLQPGQ AVQTLNDRMK RINKINLEIA DWLQERRRVE EQYVLGMRKL
     AQFKSPNAQS ELGVFQLPWS RIIESVERIA QSHQLFADRL GNDVEQPLRG FPQRQDVQNM
     ANISNNLTVM ARELDDARDK SDKLTKKGGK ASTQKVDAAS SKLESATQQW ESQSPFIFET
     LQVLDESRVN LLRDLLTQFQ THESDRAQRD SDISVETLAM MLEISTEREV QSFVQKVTAG
     KAQLPPSRTA TRRSTTHMSQ NSAASQPSVP STPNTSQPPQ EDDASEHNSV LNSEAKPESK
     LRRLGTMFGG RRRQSVHAGF GSLSPQKTPG PTFGRLGSSH GRGVSPMTSS SNLHENNRLS
     ILPEMPDQAR RPQSSSDAMH RDRGEEGGPS TNGNTNGFGA GESLLDTQAP DMPSSSVTNG
     NVNVEQQQQQ QQFQQQQQPE AAAVNPPPSQ QSQQEPVSPT SKDEEGFTIR APMNDPISEA
     QREAAADEND QLFKLNIQNK PIEEEDPEAA QAALSSVANT LKMGSINRRS MTVRGRRDVR
     NTIYAPVLHF PESYSDNAIP AMPAIPSSPP RPPSSRPAAV AALASEASAA SDTQSVRSGN
     SLGSAHPKHP ELTAPGLNAS IIETVSVLFE GGMLKSTSVA GEIAFANNPT ADADSAKTHE
     TIRINNFANL ERIGPNRIFV HNASPDQPDQ FALDLSHISK TATAFSYRVF ADESETPSLG
     QHAPLLINPA WKPQGDKLGL LLQYQLNPEC KWTAPVTLHN VVFVVSYEGR ATGAQTKPSG
     THLKDKHLVY WRLGDVTLTE VTQKIVCRIV GADGVEPQPG HVEARWEYAV SGEDVVGSGI
     SISRLEAVPS KDAVESDPFA DENPASSNPS LVEPTWVDVP VTRKLVSGKY EGK
//