ID A0A0F9XQD7_TRIHA Unreviewed; 930 AA.
AC A0A0F9XQD7;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=THAR02_05418 {ECO:0000313|EMBL:KKP02463.1};
OS Trichoderma harzianum (Hypocrea lixii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=5544 {ECO:0000313|EMBL:KKP02463.1, ECO:0000313|Proteomes:UP000034112};
RN [1] {ECO:0000313|Proteomes:UP000034112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T6776 {ECO:0000313|Proteomes:UP000034112};
RX PubMed=26067977; DOI=10.1128/genomeA.00647-15;
RA Baroncelli R., Piaggeschi G., Fiorini L., Bertolini E., Zapparata A.,
RA Pe M.E., Sarrocco S., Vannacci G.;
RT "Draft whole-genome sequence of the biocontrol agent Trichoderma harzianum
RT T6776.";
RL Genome Announc. 3:E0064715-E0064715(2015).
CC -!- SIMILARITY: Belongs to the SH3RF family.
CC {ECO:0000256|ARBA:ARBA00008649}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKP02463.1}.
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DR EMBL; JOKZ01000149; KKP02463.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F9XQD7; -.
DR OMA; NNCVNQG; -.
DR OrthoDB; 1462937at2759; -.
DR Proteomes; UP000034112; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR16079:SF4; E3 UBIQUITIN-PROTEIN LIGASE CHFR; 1.
DR PANTHER; PTHR16079; UBIQUITIN LIGASE PROTEIN CHFR; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000034112};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 16..72
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 868..929
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 98..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 153..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 495..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..140
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..196
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..231
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..310
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..344
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..433
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 930 AA; 103584 MW; 3F77057BF508F49E CRC64;
MESRKPSFDL GKELTCSICT ELLYQPLTLL DCLHTYCGAC LKEWFRFQAE KVGRAPTPPP
PDAIIFTCPS CRSSVRDTRH NATVATLLDM YTAANPAKAR SEADKQEMEE KYKPGDQVLP
KVKTRERTAE EKRAEEEDRR LIDEVREMSL REAVAAATPD TQQARSARRH AEGRSSDGRA
RSGSDYRSDG RSQRARDGRG GNGQSNSEHL AVEGDSQSRR RRSESRQRQV EHQSSLRSLI
GSEMSERDIE REIEEFARQI QEEGLLDGLD LDNIDLSRDD ELSQRITEAY RRRQRGRSRQ
ESERRAETRA NDNATSTSRD SRLRPDNARP QSRHRAHSRS TSEVGDRNRP PVSPSANLGV
REPERRTRRR TTSGGHHPTL PVGSSLSAID TRPAAHSQND LVLRRDPNEF DPTASVPALR
IGRSSSSTTV PAAAAAQPAE RPAIGNGKIA SFASRAQSYP SASSTPNSIN SELMEITAGR
NSKSSRLTEV VISPPDSLVS SPIQSPTAAT SLHQPPRSQQ LYEEPSISCS RCKRPDIQYD
VHYNCKACND GHWNMCIDCY RSGKGCLYWF GFGYGAWKKW EKRKQADESI PMPHMLNAGR
YKQPASTTVS ADGKKKLTTD DPRLRLETGT FCSGCFAWTN DCFWRCDFCN EGDWGFCNNC
VNQGKSCSHR LLPLAHEGTF KSTYEPRSPR SGGRPSTATV ITGAQLPGIG PFKPLIFNSK
CDICKDAIPP SSTRYHCFSC SSSAVQDATP GDYDICTSCY GNLESKGDIS EENGSSGWRR
CLSGHRMVIV GFIEGKLGQW RYVERDLVGG KALRSEPLEN IAHPDFQKWS WHDGEEKEDR
LVATDVSSTA PESFGEISYA RTFPPDGGSG QVAHAMWSWY PKSGAEDELM FPRGAEIQEI
RDINGDWFFG TYMGAKGLFP APYVKLPQQS
//
