ID A0A0F9ZR77_TRIHA Unreviewed; 1515 AA.
AC A0A0F9ZR77;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Brefeldin A resistance protein {ECO:0000313|EMBL:KKP02822.1};
GN ORFNames=THAR02_05052 {ECO:0000313|EMBL:KKP02822.1};
OS Trichoderma harzianum (Hypocrea lixii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=5544 {ECO:0000313|EMBL:KKP02822.1, ECO:0000313|Proteomes:UP000034112};
RN [1] {ECO:0000313|Proteomes:UP000034112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T6776 {ECO:0000313|Proteomes:UP000034112};
RX PubMed=26067977; DOI=10.1128/genomeA.00647-15;
RA Baroncelli R., Piaggeschi G., Fiorini L., Bertolini E., Zapparata A.,
RA Pe M.E., Sarrocco S., Vannacci G.;
RT "Draft whole-genome sequence of the biocontrol agent Trichoderma harzianum
RT T6776.";
RL Genome Announc. 3:E0064715-E0064715(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKP02822.1}.
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DR EMBL; JOKZ01000134; KKP02822.1; -; Genomic_DNA.
DR OMA; RTSMRHD; -.
DR OrthoDB; 5473955at2759; -.
DR Proteomes; UP000034112; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010929; PDR_CDR_ABC.
DR PANTHER; PTHR19241:SF682; ABC MULTIDRUG TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF06422; PDR_CDR; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000034112};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 525..545
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 557..578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 598..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 634..652
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 664..684
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 769..789
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1206..1226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1276..1302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1314..1336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1348..1369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1472..1492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 163..421
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 870..1113
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 816..843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..75
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 822..836
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1515 AA; 169286 MW; 1973FB4467004954 CRC64;
MSKDLDPMDL KETGGRPPQA SSGEAITTLP NESGQSADKK EQDDSSLVGS RISSSSDDSS
TSGHRMTSRV PSHASVQNED DLFRVLSRRR TTGSGGSGTE GVEDSAEIER LMSRMFGHAR
QEQNPEENLR HSGVIFRDLT VKGVGLGASL QPTVGDILLG LPRKIRNLIR GGRKAAQAKP
PIRELISHFD GCVRPGELLL VLGRPGSGCS TFLKAFCNQR YGFQAVEGDV KYGGTDAKEI
AKHFRGEVIY NPEDDLHYAT LTVKRTLSFA LQTRTPGKEA RLEGESRSSY IKEFLRVVTK
LFWIEHTLGT KVGNEFIRGV SGGERKRVSI AEAMITRASV QGWDNSSKGL DASTALEYVR
AIRAMTNMGK ISTSVSLYQA GESLYELVDK VLLIDGGKCL YFGPSEKAKK YFLDLGFDCP
ERWTTADFLT SVSDQHERSI RPGWEQRIPR SPDEFFNAYR KSEIYRENIA DMEAFEKELH
TQAEEREAAH RKKIEHNYTL AFHQQVIACT KRQFLIMIGD SASLFGKWGG LLFQGLIVGS
LFFNLPETAA GAFPRGGTLF FLLLFNALLA LAEMTAAFTS KPIMLKHKSF SFYRPAAYAV
AQTVVDVPLV FIQIVLFNTI IYFMSHLSRT ASQYFIATLI LWLVTMVTYA FFRCLAAWCP
TLDEATRVTG VAVQILIVYT GYLIPPSQMH PWFSWLRWIN WIFYGFECLM SNEFTGLQLE
CVPPYLVPQG PGTSPQFQSC TLAGSQPGQT TVDGAAYIKS AFSYTRAHLW RNFGFLWAFF
IFFVFMTAVG MEIMKPNAGG GAITMFKRGQ VPKAVETSIE TGGRGQEKKK TDEESGVVSH
ITPAMVQEKE LENSDSTGDG PEIAKNETVF TFRNINYTIP YQKGEKKLLQ DVQGYVRPGK
LTALMGASGA GKTTLLNALA QRLRFGTVNG EFLVDGRPLP KSFQRATGFA EQMDIHEPTS
TVREALQFSA LLRQPHEVPR TEKLAYCETI IDLLEMKDIA GATIGKIGQG LNQEQRKRLT
IGVELASKPE LLMFLDEPTS GLDSGAAFNI VRFLRKLADA GQAVLCTIHQ PSAVLFEHFD
ELLLLKNGGR VVYHGALGKD SQPLIRYFES NGAHRCPPNA NPAEYMLDAI GAGDPNYHGQ
DWGDVWAASP EHDERSREIQ DMISARQKVE LSKNLKDDRE YAAPLSLQTT LVVKRAFVSY
WRAPNYIVGK FMLHILTGLF NCFTFWRLGY STIAYQSRLF SIFMTLTISP PLIQQLQPVF
LNSRNLFQSR ENNAKIYSWL AWVTSAIVVE IPYGLVAGAI YFNCWWWGIF GTRVSGFTSG
FSFLLMMVFE LYYISFGQAI ASFAPNELMA SLLVPVFFLF VVSFCGVVVP PRQLPTFWRS
WMYWLSPFHY LLEAFLGASI HDHPVQCSSS EFARFSAPPG QTCESYTASF VNQSGGYVQT
AADGLCEFCQ YATGDQFGLG FSVEYSHIWR DFGIFCGFIA FNYGVVYFST WLKFSARNPF
RIVMTKLGRN SHRAD
//
