ID A0A0G0A8P5_9BACT Unreviewed; 484 AA.
AC A0A0G0A8P5;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=UR38_C0003G0036 {ECO:0000313|EMBL:KKP47631.1};
OS Candidatus Woesebacteria bacterium GW2011_GWA2_33_28.
OC Bacteria; Candidatus Woesebacteria.
OX NCBI_TaxID=1618561 {ECO:0000313|EMBL:KKP47631.1, ECO:0000313|Proteomes:UP000033995};
RN [1] {ECO:0000313|EMBL:KKP47631.1, ECO:0000313|Proteomes:UP000033995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC translocating in the 3'-5' direction.; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034617};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00560}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKP47631.1}.
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DR EMBL; LBOZ01000003; KKP47631.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0A8P5; -.
DR PATRIC; fig|1618561.3.peg.420; -.
DR Proteomes; UP000033995; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR CDD; cd18807; SF1_C_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 1..148
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 149..374
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
SQ SEQUENCE 484 AA; 55774 MW; E1F6A1F6E439A017 CRC64;
MEIGIKDTIK PSSVLYSISE AKNQMLEPTD QTISTIYKAY ERKLKEINAL DFDDLLIKTV
LLFEIPEIVS KWRDRLKQIF VDEWQDTNKI QYKLIRLIDG NRGVITAVGD ASQSVYSWRG
ADYRNINYLI SDYPKIKVIN LEQNYRSTQN ILEAANAVIS KNMTHPILKL WTEKESGEKI
SIYPARNGFD EAEFVINEIK RLVLSGKDYS DVAILYRTNA QSRVLEEALL HASIPYSLMG
GVRFYDRKEI KDILSYLRLL VNHKDTVSKK RVLALGKRRY EAFSNLQLSI SNLQELTTLE
ILDQVLKTTS YLAKFKEIDP EDVERLENIK ELRSVAIEFP TLIEFLENVS LIEAGPIHET
KNAVTLMTLH SAKGLEFTVV FIVGMEEGIF PHSRSLWEKE QLEEERRLCY VGITRAKETL
ILCYASKRLF YGETSSNAPS RFLSDIPEHL LNGSLEIIKN DVYNDSQIAD DDLNFDNILD
KYLK
//
