ID A0A0G0ARQ0_TRIHA Unreviewed; 804 AA.
AC A0A0G0ARQ0;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Patatin-like phospholipase domain-containing protein {ECO:0000256|RuleBase:RU362055};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU362055};
GN ORFNames=THAR02_00710 {ECO:0000313|EMBL:KKP07174.1};
OS Trichoderma harzianum (Hypocrea lixii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=5544 {ECO:0000313|EMBL:KKP07174.1, ECO:0000313|Proteomes:UP000034112};
RN [1] {ECO:0000313|Proteomes:UP000034112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T6776 {ECO:0000313|Proteomes:UP000034112};
RX PubMed=26067977; DOI=10.1128/genomeA.00647-15;
RA Baroncelli R., Piaggeschi G., Fiorini L., Bertolini E., Zapparata A.,
RA Pe M.E., Sarrocco S., Vannacci G.;
RT "Draft whole-genome sequence of the biocontrol agent Trichoderma harzianum
RT T6776.";
RL Genome Announc. 3:E0064715-E0064715(2015).
CC -!- FUNCTION: Lipid hydrolase. {ECO:0000256|RuleBase:RU362055}.
CC -!- FUNCTION: Probable lipid hydrolase. {ECO:0000256|ARBA:ARBA00002682}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362055}; Single-
CC pass membrane protein {ECO:0000256|RuleBase:RU362055}.
CC -!- SIMILARITY: Belongs to the PLPL family.
CC {ECO:0000256|RuleBase:RU362055}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKP07174.1}.
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DR EMBL; JOKZ01000011; KKP07174.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0ARQ0; -.
DR OMA; CLMGERA; -.
DR OrthoDB; 154387at2759; -.
DR Proteomes; UP000034112; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006641; P:triglyceride metabolic process; IEA:UniProt.
DR CDD; cd07230; Pat_TGL4-5_like; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002641; PNPLA_dom.
DR InterPro; IPR021771; Triacylglycerol_lipase_N.
DR PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR PANTHER; PTHR14226:SF10; TRIACYLGLYCEROL LIPASE 4-RELATED; 1.
DR Pfam; PF11815; DUF3336; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU362055};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963,
KW ECO:0000256|RuleBase:RU362055};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098,
KW ECO:0000256|RuleBase:RU362055};
KW Reference proteome {ECO:0000313|Proteomes:UP000034112}.
FT DOMAIN 223..420
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 596..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 729..795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..698
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 737..753
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 804 AA; 89378 MW; B22B40C423E475DB CRC64;
MADFFLRAPP IPQIHTGSTS PPSPKRQKQV SASSQPLQPA DRTIVQTVSQ TVKGAASYLR
SWKDGVSPEE REKARLLEER KNILCLRMKS AETLKQWQAA AQELDVLEGN DDWRRDNESD
DYNSRLIEER LRALDEARES RDIRTMMHLI RTALSRDLGG MGNVDLYRHS YLGTKTLIER
YVESTIETID AAIVHSATDQ GIAYKDLLEG MLLARQSFGR SALLLSGGGT FGMAHVGVLK
ALFENQLLPR IISGASAGSI VCAVMCTRTD EEIPQLIKEF PYGDLAVFEA QDNQDGLLDH
FRRLLTEGCW SDIAHLRRVM RGMMGDITFQ EAYNRTRRIL NICVSSASVY ELPRLLNYVT
SPNVMIWSAV AASCSVPLIF NSSPLLVKDP VTGEHRQWNP SPQRFIDGSV DNDLPMTRLA
EMFNVNHFIV SQVNPHVTPF LAKDDHLSPE NQHTHKSAKN GGDDMDWIYA CTSLARDEAL
HRLQFMAEMG FFPNMMTKFR SILSQKYSGN INILPDLTLD NLPVLLRNPS VDFMLKCCLV
GERATWPKLS RIRDSCAIEL ALDRAVHRLR TRVVFSESQS NLRSIVSYMG GLRLNKHDQT
PNQANLGVPI ASHGQKRQRR RSGGSLLLPG PGLVLDTDLT DEETAEEERL EIASRRHGLA
SSTSLRKPQL KRSALSQTHV PQLSASQSQS NPRFNFSKPI TPPASVHGEI DVVDTANINY
LDPRAPVTFS DAGDSRVEPS LGSSISPVDE IETSEPNHTS DTEVEQGTEE SDPDDSQSAP
VEDTPKPANY GAFGPAGEVI GGFW
//
