ID A0A0G0C8S1_9BACT Unreviewed; 425 AA.
AC A0A0G0C8S1;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 13-SEP-2023, entry version 20.
DE SubName: Full=Nucleotide sugar dehydrogenase {ECO:0000313|EMBL:KKP77578.1};
GN ORFNames=UR78_C0035G0004 {ECO:0000313|EMBL:KKP77578.1};
OS Candidatus Moranbacteria bacterium GW2011_GWF2_35_39.
OC Bacteria; Candidatus Moranbacteria.
OX NCBI_TaxID=1618721 {ECO:0000313|EMBL:KKP77578.1, ECO:0000313|Proteomes:UP000034839};
RN [1] {ECO:0000313|EMBL:KKP77578.1, ECO:0000313|Proteomes:UP000034839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKP77578.1}.
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DR EMBL; LBQM01000035; KKP77578.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0C8S1; -.
DR PATRIC; fig|1618721.3.peg.1063; -.
DR Proteomes; UP000034839; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 317..409
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 425 AA; 47453 MW; AF5412F5EC5D36D7 CRC64;
MQKNKKHSEV VAVIGLGYVG LPLAIRTAEK GYKVFGFDLD KKKIQAIQKG QSPFKEEFIE
KRKSPVVLQK ADIVIVCVPT PVDEKFYPIF EPLISAVELI IKNKKAGQLI VIESTINPGV
CEEVLMPLFQ KAKLIEGKDY FLAHCPERIN PGKDAISHGY NVSNIARVVG ASSKKGLIWA
KNFYQSIIDA PIKAMGSIKE AEACKVVENS FRDINIAFVN ELAKSFAKMD IDVKNVIEGA
ATKPFAFMAH YPSRGVGGHC IPVDPYYLIE RAKQNGFDHK FLRSAREINN SMPAYTVELM
HDLLNELKLP IKDTAVGVMG LSYKANVDDL RESPAVKIIK ELENKGARVI RFDPFIPSMS
DVKNLEDFLK KSTAIIFVTN HKVFSAIKPQ TFKKFGIRAI VDGVNSLDKE KIKKLGIKYR
GIGRR
//
