ID A0A0G0DFZ8_9BACT Unreviewed; 443 AA.
AC A0A0G0DFZ8;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 08-NOV-2023, entry version 33.
DE RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
DE Flags: Fragment;
GN ORFNames=UR94_C0001G0043 {ECO:0000313|EMBL:KKP92358.1};
OS Parcubacteria group bacterium GW2011_GWA2_36_10.
OC Bacteria.
OX NCBI_TaxID=1618808 {ECO:0000313|EMBL:KKP92358.1, ECO:0000313|Proteomes:UP000034083};
RN [1] {ECO:0000313|EMBL:KKP92358.1, ECO:0000313|Proteomes:UP000034083}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- FUNCTION: Plays an important role in the initiation and regulation of
CC chromosomal replication. Binds to the origin of replication; it binds
CC specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-
CC TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
CC {ECO:0000256|RuleBase:RU000577}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|ARBA:ARBA00006583,
CC ECO:0000256|RuleBase:RU004227}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKP92358.1}.
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DR EMBL; LBRC01000001; KKP92358.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0DFZ8; -.
DR STRING; 1618808.UR94_C0001G0043; -.
DR PATRIC; fig|1618808.3.peg.44; -.
DR Proteomes; UP000034083; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd06571; Bac_DnaA_C; 1.
DR Gene3D; 1.10.1750.10; -; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.300.180; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00377; DnaA_bact; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR001957; Chromosome_initiator_DnaA.
DR InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR InterPro; IPR013317; DnaA.
DR InterPro; IPR013159; DnaA_C.
DR InterPro; IPR024633; DnaA_N_dom.
DR InterPro; IPR038454; DnaA_N_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010921; Trp_repressor/repl_initiator.
DR NCBIfam; TIGR00362; DnaA; 1.
DR PANTHER; PTHR30050; CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA; 1.
DR PANTHER; PTHR30050:SF2; CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA; 1.
DR Pfam; PF00308; Bac_DnaA; 1.
DR Pfam; PF08299; Bac_DnaA_C; 1.
DR Pfam; PF11638; DnaA_N; 1.
DR PRINTS; PR00051; DNAA.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00760; Bac_DnaA_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48295; TrpR-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU000577};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU000577};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU000577};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000577}.
FT DOMAIN 169..304
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 378..443
FT /note="Chromosomal replication initiator DnaA C-terminal"
FT /evidence="ECO:0000259|SMART:SM00760"
FT NON_TER 443
FT /evidence="ECO:0000313|EMBL:KKP92358.1"
SQ SEQUENCE 443 AA; 49767 MW; 5004421F104E3DBD CRC64;
MPIGLEQSST IIKVFPRKGV SSDTDANSIL LEILAELKMS VPAQQFDIWF SCLRIFSIDE
SSITFITPNN FIKDWFSSNY KDLFSGAAYR VLNSSREIVF LAEDEALRQS QASSASSCDT
PKSIRELPAN NGQANSLNGY YRFENFIVGP CNRLAHAAAV AVSESPGIAY NPLFIHGASG
LGKTHLLHAI NNVLLPKRTI RTLYLSCEQF VNHFISTMRS NNWDEFRNLY RNLDVLLLDD
IQFFENLQGC REEFFHTFNA LYNAKKQIVI TSDCPPESLN SLEDRLVSRF KWGLLCSVDS
PTIETRVAII EKNASLMNIN LTHDFASYLA EHLPGNIREL EGAIVRLGKE LKVTRNTMTL
DFIKKVLHEI TGNKQSVAIE AILRAVSDRF NVSISQLQSK SRSRSLTLPR QIAMYLSRKL
TNMSLTEVGG FLGGRDHSTV IHA
//
