ID A0A0G0HK39_9BACT Unreviewed; 425 AA.
AC A0A0G0HK39;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=US54_C0001G0055 {ECO:0000313|EMBL:KKQ38930.1};
OS Candidatus Roizmanbacteria bacterium GW2011_GWA2_37_7.
OC Bacteria; Candidatus Roizmanbacteria.
OX NCBI_TaxID=1618481 {ECO:0000313|EMBL:KKQ38930.1, ECO:0000313|Proteomes:UP000034471};
RN [1] {ECO:0000313|EMBL:KKQ38930.1, ECO:0000313|Proteomes:UP000034471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00560}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKQ38930.1}.
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DR EMBL; LBTJ01000001; KKQ38930.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0HK39; -.
DR STRING; 1618481.US54_C0001G0055; -.
DR Proteomes; UP000034471; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 1..118
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 114..367
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
SQ SEQUENCE 425 AA; 49839 MW; BB5F1621E0E0D065 CRC64;
MKIDVVEKQE NKKANVHNQF TYDELIQKTR ELLNAKEPKI NKWRSRFSHI LIDEFQDTNV
MQFEIVKNLL HTENLYVIGD PYQSIYGFRG ADPSIFQIIC VDFQNVSEIT LTQNYRSGQN
IIDVSHNLFP SSKRLLSMID SQGAVQYIIT QNEKTESRWI LKDIQNHIGG ADLLQASDNR
SNDQNYRFSD FAVIFRTHHI GRILEGYFCK ESIPYQMIGG DSLFERPHIY AITSAMKTLL
KEGDTKAKVS NIIRMIVENK TIETMIKHSE QKQTDVQHFV SMMCQFDRYE DGLFQAIQHI
TYLEEHEYYD YQADKVTLLT MHAAKGLEFA HVYIAGFEEG MIPLIRGDID SEEEKRLLYV
AMTRAKKTLS LIRPKYRFGK NTQETRFCRM LAKNPAFQKK IDKEIVAGEK RRKKWFDKKS
QMKMF
//
