ID A0A0G0IPN3_9BACT Unreviewed; 634 AA.
AC A0A0G0IPN3;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=US39_C0002G0030 {ECO:0000313|EMBL:KKQ26104.1};
OS Microgenomates group bacterium GW2011_GWC1_37_12b.
OC Bacteria.
OX NCBI_TaxID=1618510 {ECO:0000313|EMBL:KKQ26104.1, ECO:0000313|Proteomes:UP000034251};
RN [1] {ECO:0000313|EMBL:KKQ26104.1, ECO:0000313|Proteomes:UP000034251}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC translocating in the 3'-5' direction.; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034617};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKQ26104.1}.
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DR EMBL; LBSU01000002; KKQ26104.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0IPN3; -.
DR STRING; 1618510.US39_C0002G0030; -.
DR PATRIC; fig|1618510.3.peg.254; -.
DR Proteomes; UP000034251; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR CDD; cd18807; SF1_C_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 9..286
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 287..524
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 30..37
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 634 AA; 72578 MW; 81BB4FC75634976D CRC64;
MTNTDKLLDS LNDAQKKAVT YKNGPLLVLA GAGSGKTKVL THRAAYFIQE KIAHPSEILL
LTFTNKAAYE MKERIGLLTQ DIPGFTGTFH SFCVKLLRHD GKILGIPPGF VIYDDEDQKD
AVKEIINKLN LNDEKFKPSE VLYQISDAKT NMLGPLAYGE IAQGDWQATV FKIYLEYEKF
LKESGALDFD DLLLKTVKLL DENKEIKNKW QENYKYVLVD EWQDTNKIQY KLTKLLVGDR
KNLTAVGDAA QSIYSWRGAD YRNINNLIKD YPEMSVINLE RNYRSTQNIL DAANSIIKKN
SSHPVLSLWT DKKAGQKIKI YRGRSELDEA GFIISQIDNL ITKGIEFNDI AVLYRTNAQS
RVIEEALLHA GIPYSLVGGV KFYSRKEIKD VLSYLRLIAN PKDKVSRARI EKLGVKKYEN
FQKFEESLEK IEGLTTLDLM DQVLNKTDYL SKYIRETEEN LARLENIKEL RSVAAEFPDL
NEFLENVALI EAEQDENGKV KSRSSSDQTP RNCITLMTLH AAKGLEFGVV FIIGMEEGLF
PHSRSLFDIN QLEEERRLAY VGITRAKEIL YLTYAGRRLY FGQKTSNPPS RFIIDIPEEL
LEGIEGEYLE RNSFKKQHSY DYDAIDDFDD SINF
//
