ID A0A0G0J6J5_9BACT Unreviewed; 309 AA.
AC A0A0G0J6J5;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=inorganic diphosphatase {ECO:0000256|ARBA:ARBA00012146};
DE EC=3.6.1.1 {ECO:0000256|ARBA:ARBA00012146};
DE AltName: Full=Pyrophosphate phospho-hydrolase {ECO:0000256|ARBA:ARBA00032535};
GN ORFNames=US82_C0003G0037 {ECO:0000313|EMBL:KKQ63088.1};
OS Parcubacteria group bacterium GW2011_GWC1_38_22.
OC Bacteria.
OX NCBI_TaxID=1618897 {ECO:0000313|EMBL:KKQ63088.1, ECO:0000313|Proteomes:UP000034773};
RN [1] {ECO:0000313|EMBL:KKQ63088.1, ECO:0000313|Proteomes:UP000034773}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=diphosphate + H2O = H(+) + 2 phosphate; Xref=Rhea:RHEA:24576,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:43474; EC=3.6.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000926};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKQ63088.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LBUL01000003; KKQ63088.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0J6J5; -.
DR STRING; 1618897.US82_C0003G0037; -.
DR PATRIC; fig|1618897.3.peg.146; -.
DR Proteomes; UP000034773; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004427; F:inorganic diphosphate phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.10.310.20; DHHA2 domain; 1.
DR Gene3D; 3.90.1640.10; inorganic pyrophosphatase (n-terminal core); 1.
DR InterPro; IPR001667; DDH_dom.
DR InterPro; IPR038763; DHH_sf.
DR InterPro; IPR004097; DHHA2.
DR InterPro; IPR038222; DHHA2_dom_sf.
DR PANTHER; PTHR12112; BNIP - RELATED; 1.
DR PANTHER; PTHR12112:SF22; MANGANESE-DEPENDENT INORGANIC PYROPHOSPHATASE; 1.
DR Pfam; PF01368; DHH; 1.
DR Pfam; PF02833; DHHA2; 1.
DR SMART; SM01131; DHHA2; 1.
DR SUPFAM; SSF64182; DHH phosphoesterases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 180..307
FT /note="DHHA2"
FT /evidence="ECO:0000259|SMART:SM01131"
SQ SEQUENCE 309 AA; 34709 MW; 151C3C3DC7E9BEDC CRC64;
MSKIIIVGHK NPDTDSVVSS IAAQEYFEKV LGKESKAYCA GMLNNETKFI LEKLEVEIPK
LFEKIEDDEC AAIVDHNQPS QIVDGLDYGK IEYIFDHHNL NIVTEKPIFV RVEPIGSTSS
LIAKMFFEKG ITPSEVTSKL LLSGILSDML NFTSPTTTDE DRKLADKLNE IAKLDMQEFV
TEMFKAKSSL EGISIEDVIT LDYKTFEMGS KNVGIGTWET TLPESVNIKK DEIFAALEKK
KALENLDYMF FMVVDILQGN CQLYIIGDAE KELAEKVFGK EAENKLMTLP GVVSRKKQIV
PQLTEELSK
//
