ID   A0A0G0L0A8_9BACT        Unreviewed;       283 AA.
AC   A0A0G0L0A8;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=UDP-glucose dehydrogenase (Ugd-1) {ECO:0000313|EMBL:KKQ84442.1};
GN   ORFNames=UT08_C0018G0048 {ECO:0000313|EMBL:KKQ84442.1};
OS   Candidatus Woesebacteria bacterium GW2011_GWB1_38_8.
OC   Bacteria; Candidatus Woesebacteria.
OX   NCBI_TaxID=1618570 {ECO:0000313|EMBL:KKQ84442.1, ECO:0000313|Proteomes:UP000034081};
RN   [1] {ECO:0000313|EMBL:KKQ84442.1, ECO:0000313|Proteomes:UP000034081}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT   radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00006601, ECO:0000256|PIRNR:PIRNR000124}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKQ84442.1}.
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DR   EMBL; LBVL01000018; KKQ84442.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G0L0A8; -.
DR   STRING; 1618570.UT08_C0018G0048; -.
DR   PATRIC; fig|1618570.3.peg.1285; -.
DR   Proteomes; UP000034081; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR017476; UDP-Glc/GDP-Man.
DR   InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR   InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR   InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR   PANTHER; PTHR43750; UDP-GLUCOSE 6-DEHYDROGENASE TUAD; 1.
DR   PANTHER; PTHR43750:SF3; UDP-GLUCOSE 6-DEHYDROGENASE TUAD; 1.
DR   Pfam; PF00984; UDPG_MGDP_dh; 1.
DR   Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR   PIRSF; PIRSF500136; UDP_ManNAc_DH; 2.
DR   PIRSF; PIRSF000124; UDPglc_GDPman_dh; 2.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
FT   DOMAIN          35..145
FT                   /note="UDP-glucose/GDP-mannose dehydrogenase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03721"
FT   DOMAIN          166..258
FT                   /note="UDP-glucose/GDP-mannose dehydrogenase dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF00984"
SQ   SEQUENCE   283 AA;  31612 MW;  C71C1AAC23FC6745 CRC64;
     MANIGIIGWG VVGQATGKGF KKKHNVFWNS PHKEDSTSIK DVADKCEYIF LCLPTPADFQ
     NYKIDLSIIN KVVSDFAPLV KGRNKALIIK STVVPGTTAK FAKKYPGVKF AMNPEFLTEI
     NAPWDFLHPD RVVIGAYDED VANKIARLHR DILGYKVKIF ITDPTTAELV KYMSNTFMAT
     KIIFGNEFAE LSGKLGVNYD EVVAMVGADK RILPSFFKKT SFAGFGGKCF PKDTVSILGL
     AKELGVNLSV LEAAWKKNLK VRKIRDWEEI RGAVNKREVR IKM
//