ID A0A0G0M900_9BACT Unreviewed; 330 AA.
AC A0A0G0M900;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN ORFNames=US90_C0008G0016 {ECO:0000313|EMBL:KKQ70124.1};
OS Candidatus Shapirobacteria bacterium GW2011_GWE2_38_30.
OC Bacteria; Candidatus Shapirobacteria.
OX NCBI_TaxID=1618490 {ECO:0000313|EMBL:KKQ70124.1, ECO:0000313|Proteomes:UP000034406};
RN [1] {ECO:0000313|EMBL:KKQ70124.1, ECO:0000313|Proteomes:UP000034406}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC {ECO:0000256|ARBA:ARBA00009009}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKQ70124.1}.
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DR EMBL; LBUT01000008; KKQ70124.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0M900; -.
DR STRING; 1618490.US90_C0008G0016; -.
DR Proteomes; UP000034406; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251}.
FT DOMAIN 91..303
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 330 AA; 37349 MW; 984ACDA94B4D546D CRC64;
MMNIKGYKVW IKYLLITTVA FLMGFISKSI IDPILQTTVT ETRNSQNYRF INPLLECESS
NFSQNAALQP LRNQLNDSIE NTDNKQVSHV SVYYRDLNNG PWIGIDEKEN FSPASLVKVP
LMIAYFKAAE TDPGLLGQTI PVPGTFNHQQ TILPQITLTP NQTYTVEELI NRMIIYSDNQ
AYELLQEYID NQILVKTYTD LGIDISQAYD DPTGNIISVK SYASFFRILF NASYLNKDTS
EKALKLLSQT KYDQGIVKGV ADPLISVSNK FGERTYLETG ERQLHDCGIV YAPAKPYLLC
IMTRGSNFPL MEKIINDVSS LVFQTVNSQI
//
