ID A0A0G0NPJ5_9BACT Unreviewed; 99 AA.
AC A0A0G0NPJ5;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Gyrase subunit A protein {ECO:0000313|EMBL:KKR14691.1};
DE Flags: Fragment;
GN ORFNames=UT44_C0053G0001 {ECO:0000313|EMBL:KKR14691.1};
OS Candidatus Levybacteria bacterium GW2011_GWA1_39_32.
OC Bacteria; Candidatus Levybacteria.
OX NCBI_TaxID=1618454 {ECO:0000313|EMBL:KKR14691.1, ECO:0000313|Proteomes:UP000034624};
RN [1] {ECO:0000313|EMBL:KKR14691.1, ECO:0000313|Proteomes:UP000034624}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrA/ParC subunit
CC family. {ECO:0000256|ARBA:ARBA00008263}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKR14691.1}.
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DR EMBL; LBWU01000053; KKR14691.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0NPJ5; -.
DR Proteomes; UP000034624; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR Gene3D; 3.90.199.10; Topoisomerase II, domain 5; 1.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR013758; Topo_IIA_A/C_ab.
DR InterPro; IPR002205; Topo_IIA_dom_A.
DR PANTHER; PTHR43493:SF5; DNA GYRASE SUBUNIT A, CHLOROPLASTIC_MITOCHONDRIAL; 1.
DR PANTHER; PTHR43493; DNA GYRASE/TOPOISOMERASE SUBUNIT A; 1.
DR Pfam; PF00521; DNA_topoisoIV; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 30..99
FT /note="DNA topoisomerase type IIA"
FT /evidence="ECO:0000259|Pfam:PF00521"
FT NON_TER 99
FT /evidence="ECO:0000313|EMBL:KKR14691.1"
SQ SEQUENCE 99 AA; 11241 MW; 5673AE85A6BAFBEA CRC64;
MEIGKLKQTD IAEEMKRAYL DYAMSVIVSR ALPDVRDGLK PVHRRILFAM DEMGLAHTAK
YSKSAKIVGE VMGKFHPHGD MPIYDALVRL AQSFSMRYP
//
