ID A0A0G0RCH9_9BACT Unreviewed; 397 AA.
AC A0A0G0RCH9;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=tyrosine--tRNA ligase {ECO:0000256|ARBA:ARBA00013160};
DE EC=6.1.1.1 {ECO:0000256|ARBA:ARBA00013160};
DE AltName: Full=Tyrosyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00033323};
GN ORFNames=UT85_C0002G0032 {ECO:0000313|EMBL:KKR50424.1};
OS Candidatus Levybacteria bacterium GW2011_GWA2_40_16.
OC Bacteria; Candidatus Levybacteria.
OX NCBI_TaxID=1618458 {ECO:0000313|EMBL:KKR50424.1, ECO:0000313|Proteomes:UP000034824};
RN [1] {ECO:0000313|EMBL:KKR50424.1, ECO:0000313|Proteomes:UP000034824}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-
CC tyrosyl-tRNA(Tyr); Xref=Rhea:RHEA:10220, Rhea:RHEA-COMP:9706,
CC Rhea:RHEA-COMP:9707, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:58315, ChEBI:CHEBI:78442,
CC ChEBI:CHEBI:78536, ChEBI:CHEBI:456215; EC=6.1.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000069};
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC {ECO:0000256|RuleBase:RU363036}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKR50424.1}.
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DR EMBL; LBYJ01000002; KKR50424.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0RCH9; -.
DR PATRIC; fig|1618458.3.peg.112; -.
DR Proteomes; UP000034824; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004831; F:tyrosine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006437; P:tyrosyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00805; TyrRS_core; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR Gene3D; 1.10.240.10; Tyrosyl-Transfer RNA Synthetase; 1.
DR InterPro; IPR001412; aa-tRNA-synth_I_CS.
DR InterPro; IPR002305; aa-tRNA-synth_Ic.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR InterPro; IPR002307; Tyr-tRNA-ligase.
DR InterPro; IPR024088; Tyr-tRNA-ligase_bac-type.
DR NCBIfam; TIGR00234; tyrS; 1.
DR PANTHER; PTHR11766:SF1; TYROSINE--TRNA LIGASE; 1.
DR PANTHER; PTHR11766; TYROSYL-TRNA SYNTHETASE; 1.
DR Pfam; PF00579; tRNA-synt_1b; 1.
DR PRINTS; PR01040; TRNASYNTHTYR.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR PROSITE; PS00178; AA_TRNA_LIGASE_I; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000256|RuleBase:RU363036};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363036};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363036};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363036};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW ECO:0000256|RuleBase:RU363036};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182}.
SQ SEQUENCE 397 AA; 45160 MW; 1BC430F71BFA6F60 CRC64;
MVDKINRILT RGVANIIPNK IELERVLNSG KKLNVYLGID PTAPRIHLGH AVPLIKLQKF
AELGHSVTLL IGDFTALIGD TSDKDSERPI LTSEEIEENF KTYKKQAEKI LDFSKIIVRH
NSEWLSKLGF KDVVELTQKF SLGDFNSREL IKRRLAGDGK VGLHEVLYPV MQGYDSYFMD
TDIQIGGTDQ TFNMQAGRHL QKLLRNKESF VMSTEFLMGT DGRKMSKTWG NAIWLDDSAR
DMVVKIMAIN DDLIIQYFTL ATQLSNEEIE KIEQRLKEGE NPIEVKKELA RTIVSGLYSE
KEAREAQEYF ERTVQKKELP EDIPIFEMKP DEHLVITDLL VKTGLVGSKS EAKRLVGQAA
VEIDSDVVDS PFEEIIPEDN MLIKCGKRNF IRIKISS
//
