ID A0A0G0RGP9_9BACT Unreviewed; 395 AA.
AC A0A0G0RGP9;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Methyltransferase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=UT41_C0001G0376 {ECO:0000313|EMBL:KKR12832.1};
OS Candidatus Wolfebacteria bacterium GW2011_GWC2_39_22.
OC Bacteria; Candidatus Wolfebacteria.
OX NCBI_TaxID=1619013 {ECO:0000313|EMBL:KKR12832.1, ECO:0000313|Proteomes:UP000034665};
RN [1] {ECO:0000313|EMBL:KKR12832.1, ECO:0000313|Proteomes:UP000034665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- SIMILARITY: Belongs to the peptidase S24 family.
CC {ECO:0000256|ARBA:ARBA00007484, ECO:0000256|RuleBase:RU003991}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKR12832.1}.
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DR EMBL; LBWR01000001; KKR12832.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0RGP9; -.
DR STRING; 1619013.UT41_C0001G0376; -.
DR PATRIC; fig|1619013.3.peg.388; -.
DR Proteomes; UP000034665; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd06529; S24_LexA-like; 1.
DR Gene3D; 2.10.109.10; Umud Fragment, subunit A; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR039418; LexA-like.
DR InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR InterPro; IPR006197; Peptidase_S24_LexA.
DR InterPro; IPR015927; Peptidase_S24_S26A/B/C.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR33516; LEXA REPRESSOR; 1.
DR Pfam; PF01555; N6_N4_Mtase; 2.
DR Pfam; PF00717; Peptidase_S24; 1.
DR PRINTS; PR00726; LEXASERPTASE.
DR SUPFAM; SSF51306; LexA/Signal peptidase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
PE 3: Inferred from homology;
KW Autocatalytic cleavage {ECO:0000256|ARBA:ARBA00022813,
KW ECO:0000256|RuleBase:RU003991}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003991};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW SOS response {ECO:0000256|ARBA:ARBA00023236};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 11..92
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
FT DOMAIN 125..252
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
FT DOMAIN 270..387
FT /note="Peptidase S24/S26A/S26B/S26C"
FT /evidence="ECO:0000259|Pfam:PF00717"
SQ SEQUENCE 395 AA; 45494 MW; A90DD48E6FB39A6F CRC64;
MSIKDFKLHP EEFDLECTTV WAFPRRGNWA THASDWRGNW APEVVRNLIL RYSSEKDHLL
DCMIGGGTTA IEAKILNRHI TCIDVNEEAL ERTRKSLEFE VENKAKQRVM KCDARDMSFI
KDNEIDFVLT HPPYADIIKY SDGQIEEDIS GIHDIDAFVD EIEKVAKELY RVLRPGKYCA
ILMGDTRRNK MYQPLAFKVM ERFLRVGFVL KEDIIKRQFN CKATGFWVNK SKESNFLLIM
HEHLFVFQKL DSIKSPDFAT VSKIKTIDVP LVGSVPCGTP LLAEENIEEV IPVEKKKLQS
GLQYFILRAS GDSMNEAGIN DGDLVLCKQK LTARENDLVV ALIDDEATVK EFHREKNKII
LKPRSTNLEH QPRYFTKGED FKIQGIVQEV VRPLD
//
