ID A0A0G0RVG0_9BACT Unreviewed; 644 AA.
AC A0A0G0RVG0;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=UT58_C0011G0004 {ECO:0000313|EMBL:KKR26505.1};
OS Microgenomates group bacterium GW2011_GWC1_39_7b.
OC Bacteria.
OX NCBI_TaxID=1618516 {ECO:0000313|EMBL:KKR26505.1, ECO:0000313|Proteomes:UP000034178};
RN [1] {ECO:0000313|EMBL:KKR26505.1, ECO:0000313|Proteomes:UP000034178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC translocating in the 3'-5' direction.; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034617};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKR26505.1}.
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DR EMBL; LBXI01000011; KKR26505.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0RVG0; -.
DR PATRIC; fig|1618516.3.peg.302; -.
DR Proteomes; UP000034178; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR CDD; cd18807; SF1_C_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 9..293
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 294..521
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 30..37
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 644 AA; 73064 MW; 70742A7E579A964F CRC64;
MNDVDKLTND LNKDQFAAVI YTAGPLLVLA GAGSGKTKVL THRVAYFIQQ GLIKPENALL
LTFTNKAATE MRQRINDLLG QSSANSKQST VFSGTFHSFC AKVLRIDGKH IGIPINFIIY
DDQDQKDAVK QILESINIST DQFAPASILN GIGEAKNQML TPAEYKNFVR GEWQEVVAKV
YEQYEKMLKD IGALDFDDLM IKTVQLFKEV PEILTKWQTT LTHIFVDEWQ DTNKIQYTLT
KLLVGKNRNI TAVGDASQSI YSWRGADYRN ITLLTRDYPD IKIVNLEQNY RSTQNILDAA
NLVISKNTNH PILKLWTDKH AGSKIKLYSA RNGFDEADFV VSEIQSRDSK YGDFAILYRT
NAQSRVLEEA FLHAGIPYSL VGGTRFYDRK EVKDIISYLK YLVNPKDSVS RKRIEKIGIR
RFEKLEEFRN SQNSLNSLTT LEMLDAVIQK TDYLSLFQKE SEENLARLEN IKELRSVATE
FPAISDFLEN VALVESTQKP ANSASIAKDS VTLMTLHAAK GLEFPIVFIV GMEEGLFPHS
RSLMDGNQLE EERRLAYVGI TRAKDVLYLT YASSRLYFGE RISNPPSRFI MDIPEDLIEN
IDANIWKDDL SSKALASEDL KLDSVEDIKG TFDDIIEKYL PHDD
//
