ID A0A0G0W5Z8_9BACT Unreviewed; 306 AA.
AC A0A0G0W5Z8;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 13-SEP-2023, entry version 32.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000256|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000256|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000256|HAMAP-Rule:MF_00073};
GN ORFNames=UU13_C0002G0017 {ECO:0000313|EMBL:KKR70672.1};
OS Candidatus Nomurabacteria bacterium GW2011_GWB1_40_7.
OC Bacteria; Candidatus Nomurabacteria.
OX NCBI_TaxID=1618744 {ECO:0000313|EMBL:KKR70672.1, ECO:0000313|Proteomes:UP000034452};
RN [1] {ECO:0000313|EMBL:KKR70672.1, ECO:0000313|Proteomes:UP000034452}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000256|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000256|ARBA:ARBA00005952,
CC ECO:0000256|HAMAP-Rule:MF_00073}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKR70672.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LBZL01000002; KKR70672.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0W5Z8; -.
DR PATRIC; fig|1618744.3.peg.85; -.
DR Proteomes; UP000034452; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription termination; IEA:UniProtKB-UniRule.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR Gene3D; 1.10.940.10; NusB-like; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR NCBIfam; TIGR01951; nusB; 1.
DR PANTHER; PTHR11078:SF3; ANTITERMINATION NUSB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11078; N UTILIZATION SUBSTANCE PROTEIN B-RELATED; 1.
DR Pfam; PF00293; NUDIX; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR SUPFAM; SSF48013; NusB-like; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00073};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00073};
KW Transcription antitermination {ECO:0000256|ARBA:ARBA00022814,
KW ECO:0000256|HAMAP-Rule:MF_00073};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00073}.
FT DOMAIN 169..300
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 306 AA; 34760 MW; 3FF8FF1982A06EF2 CRC64;
MANRHLSRSI VLQTLFEWDF QSEEKKRKNL DDEEVKEILK RNIKEFAPGF EDDGFVFSLL
EKIFKKHVTI DEIIEKAAPD WPIDKISVID RNILRIGLTE LLFGDRKEVP PKVAINEAIE
LAKTFGGENS GKFVNGVLGA VYKEIGEPGK EQISKKKKQE EIIDITKLPV EMLGGALVYK
KKNDEVLFAF VHDVFGYWTL SKGKIEAGEN EMDGTKRAIK KEIGLDIEIE EKLGENEYVA
SHPEKGKSLK KVVYFLAKSE DKELELEKSG GLDGARWFPL SAIPELRIYN DIIPLISKAI
EIISKK
//
