ID A0A0G1CYJ4_9BACT Unreviewed; 371 AA.
AC A0A0G1CYJ4;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=DNA topoisomerase (ATP-hydrolyzing) {ECO:0000256|ARBA:ARBA00012895};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
GN ORFNames=UV65_C0015G0012 {ECO:0000313|EMBL:KKS90522.1};
OS Parcubacteria group bacterium GW2011_GWF2_43_11.
OC Bacteria.
OX NCBI_TaxID=1618967 {ECO:0000313|EMBL:KKS90522.1, ECO:0000313|Proteomes:UP000034303};
RN [1] {ECO:0000313|EMBL:KKS90522.1, ECO:0000313|Proteomes:UP000034303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKS90522.1}.
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DR EMBL; LCFH01000015; KKS90522.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1CYJ4; -.
DR PATRIC; fig|1618967.3.peg.287; -.
DR Proteomes; UP000034303; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00081; Hint; 1.
DR Gene3D; 3.40.50.670; -; 1.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 1.
DR InterPro; IPR002288; DNA_gyrase_B_C.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR030934; Intein_C.
DR InterPro; IPR001241; Topo_IIA.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR013759; Topo_IIA_B_C.
DR InterPro; IPR005737; TopoIV_B_Gneg.
DR InterPro; IPR006171; TOPRIM_domain.
DR NCBIfam; TIGR01443; intein_Cterm; 1.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF00986; DNA_gyraseB_C; 1.
DR Pfam; PF14890; Intein_splicing; 1.
DR Pfam; PF01751; Toprim; 1.
DR PRINTS; PR01098; TOPISMRASE4B.
DR PRINTS; PR00418; TPI2FAMILY.
DR SMART; SM00433; TOP2c; 1.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR PROSITE; PS50818; INTEIN_C_TER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 143..166
FT /note="Intein C-terminal splicing"
FT /evidence="ECO:0000259|PROSITE:PS50818"
SQ SEQUENCE 371 AA; 42582 MW; 174B6E4CDFCEDB4E CRC64;
MKTQEEIKVV LDNDEELICT PDHKFMLRNG SYRKAKDLKP GQSLMSMPKV FINKKPAFEA
DSLETANSSN ALELSSISII ADQESLSSYQ IIKPWTAREL HPSASGRQLQ SWDYPPPTAN
TLYHSSDCNH KVVKTKILKK REDVYDLEVN ETHNFALASG IFVHNSCKMG RNRAFQAILP
LRGKILNIER ARLDKMLASK EIRALIIALG TAIGEDFNIE NLRYHRIILT LDADVDGSHI
RTLLLTFFYR HFQPIIDQGH LFIAQPPLYR IQLGKRLEYA YNEEDRAEIT SSMKKETKGN
PVIQRYKGLG EMNPEQLWET TMNPQNRILL RVDIEDAREA DHVFDILMGD DVLPRKKFIQ
AHAKKVKNLD I
//
