ID A0A0G1E8B2_9BACT Unreviewed; 475 AA.
AC A0A0G1E8B2;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KKS70813.1};
GN ORFNames=UV41_C0012G0003 {ECO:0000313|EMBL:KKS70813.1};
OS Candidatus Daviesbacteria bacterium GW2011_GWA2_42_7.
OC Bacteria; Candidatus Daviesbacteria.
OX NCBI_TaxID=1618425 {ECO:0000313|EMBL:KKS70813.1, ECO:0000313|Proteomes:UP000034785};
RN [1] {ECO:0000313|EMBL:KKS70813.1, ECO:0000313|Proteomes:UP000034785}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKS70813.1}.
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DR EMBL; LCEJ01000012; KKS70813.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1E8B2; -.
DR Proteomes; UP000034785; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 1..129
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 171..418
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 475 AA; 54725 MW; A7A9C5C0C098CB1E CRC64;
MNVLFVIKKD VYSSVEPLGI LYLSSVLKKG GHDVFLSGSS LDNISKLVKE KNIGIFAISC
MNTDYKYYLN LSQEFKKVFP KILVIWGGPT PTYNPEIINQ SAIDIICRGE GEIALLELLN
RLDNKQDYKN IPNLWVKKKS VVRKNEVGPF ISDLNSLPFP DHALIDNLPQ FKYSPIKFIM
AGRGCPFNCS FCFNHKFHEL YRGKGKMVRT RDVGNVIEEL EALKTKYNAK FFYFLDDVFP
FDRSWLTAFV KEYSRKINIP FTIVTSVVFI DDFFARHIKK AGCVSVHLAI ECGNEKLRRE
VLNKPISNEQ IINACRILKR QGISISAYNM IGIPFSKFED ELKTLDLNLK AKVDATYVSF
CLPFMDTQMG KKAFDAGLIS KDTEFLSWFE RIPIQVENRE KVEKFAHLFT LIVLFPPLRR
YLSALLSLPI PKSVLKLLKD LLNGYSLKRK IIPVKISYME FFVTAFYFIS KRFTK
//
