ID A0A0G1FVQ2_9BACT Unreviewed; 252 AA.
AC A0A0G1FVQ2;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=dolichyl-phosphate beta-glucosyltransferase {ECO:0000256|ARBA:ARBA00012583};
DE EC=2.4.1.117 {ECO:0000256|ARBA:ARBA00012583};
GN ORFNames=UV66_C0001G0215 {ECO:0000313|EMBL:KKS90858.1};
OS Candidatus Woesebacteria bacterium GW2011_GWA1_43_12.
OC Bacteria; Candidatus Woesebacteria.
OX NCBI_TaxID=1618557 {ECO:0000313|EMBL:KKS90858.1, ECO:0000313|Proteomes:UP000034669};
RN [1] {ECO:0000313|EMBL:KKS90858.1, ECO:0000313|Proteomes:UP000034669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a dolichyl phosphate + UDP-alpha-D-glucose = a dolichyl beta-
CC D-glucosyl phosphate + UDP; Xref=Rhea:RHEA:15401, Rhea:RHEA-
CC COMP:9517, Rhea:RHEA-COMP:9528, ChEBI:CHEBI:57525, ChEBI:CHEBI:57683,
CC ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.117;
CC Evidence={ECO:0000256|ARBA:ARBA00034053};
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004648}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006739}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKS90858.1}.
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DR EMBL; LCFI01000001; KKS90858.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1FVQ2; -.
DR Proteomes; UP000034669; Unassembled WGS sequence.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd04188; DPG_synthase; 1.
DR InterPro; IPR035518; DPG_synthase.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR10859:SF91; DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR10859; GLYCOSYL TRANSFERASE; 1.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Transferase {ECO:0000313|EMBL:KKS90858.1}.
FT DOMAIN 10..174
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF00535"
SQ SEQUENCE 252 AA; 28448 MW; 02E13ECD445A352E CRC64;
MIHMNKIFLS VVIPAFNEAY NLRTGVLDSV YDYLTRQKYS WEIIFVDDGS TDNTAKIAEE
FAQLRKNFFV LKEPHRGKAG TVIAGVLKSK GEIILFTDTD QATPIDQITK VLPKFENDYN
VVIGSRRGRE GAPLIRKVMA WGFSFLILMI LRLPFKDTQC GFKAFSKDAA KEIFSRLKIF
DSKNKSVGAS VTAGFDLEIL YVARKLGYKI AEVPVDWHHK EGTKVDPIKD SIEGFRGLLM
VRLNALQGKY GV
//
