ID A0A0G1IIM5_9BACT Unreviewed; 353 AA.
AC A0A0G1IIM5;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=L-threonylcarbamoyladenylate synthase {ECO:0000256|ARBA:ARBA00012584};
DE EC=2.7.7.87 {ECO:0000256|ARBA:ARBA00012584};
DE AltName: Full=L-threonylcarbamoyladenylate synthase {ECO:0000256|ARBA:ARBA00029774};
GN ORFNames=UW18_C0003G0276 {ECO:0000313|EMBL:KKT31692.1};
OS Microgenomates group bacterium GW2011_GWF1_44_10.
OC Bacteria.
OX NCBI_TaxID=1618537 {ECO:0000313|EMBL:KKT31692.1, ECO:0000313|Proteomes:UP000034538};
RN [1] {ECO:0000313|EMBL:KKT31692.1, ECO:0000313|Proteomes:UP000034538}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + hydrogencarbonate + L-threonine = diphosphate + H2O + L-
CC threonylcarbamoyladenylate; Xref=Rhea:RHEA:36407, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:17544, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:57926, ChEBI:CHEBI:73682; EC=2.7.7.87;
CC Evidence={ECO:0000256|ARBA:ARBA00001803};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the SUA5 family.
CC {ECO:0000256|ARBA:ARBA00007663}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKT31692.1}.
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DR EMBL; LCHI01000003; KKT31692.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1IIM5; -.
DR Proteomes; UP000034538; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003725; F:double-stranded RNA binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0002949; P:tRNA threonylcarbamoyladenosine modification; IEA:InterPro.
DR Gene3D; 3.90.870.10; DHBP synthase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR017945; DHBP_synth_RibB-like_a/b_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006070; Sua5-like_dom.
DR InterPro; IPR003442; T6A_TsaE.
DR NCBIfam; TIGR00057; L-threonylcarbamoyladenylate synthase; 1.
DR NCBIfam; TIGR00150; T6A_YjeE; 1.
DR PANTHER; PTHR17490; SUA5; 1.
DR PANTHER; PTHR17490:SF16; THREONYLCARBAMOYL-AMP SYNTHASE; 1.
DR Pfam; PF01300; Sua5_yciO_yrdC; 1.
DR Pfam; PF02367; TsaE; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55821; YrdC/RibB; 1.
DR PROSITE; PS51163; YRDC; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 9..198
FT /note="YrdC-like"
FT /evidence="ECO:0000259|PROSITE:PS51163"
SQ SEQUENCE 353 AA; 39120 MW; 2AE1C7D949D687BA CRC64;
MNVLIPSSID FLSQVVHILS SGGMIIYPTE TTYGLGVDAT NERAVQKLLQ YKKRRDGKPL
SIAVADIQMA EKYVVLNNVA RNVYKQFLPG PVTVISSGKH RVATFVESNH GTLGIRISSY
PLVNEIVYAF GKPITATGAN ASDQKRPYSI VDVFSFLDDT QQNLIDAVID VGELPHVEPS
TIIDTTLDNP IILRQGASPV HAKNEFISHS VDRTKELGEL CALQQKNHFG HKPIIFALRG
EMGAGKTQFV KGIASALKIA RTISSPTYVL CKEYQFEAEG KIIPCIHIDA WRLSEEHELF
SLGFEKMLQE NAVIAIEWAD RTMSALERIE REAVVVWVNI AVGSCENDRV ISW
//
