ID A0A0G1KFS5_9BACT Unreviewed; 358 AA.
AC A0A0G1KFS5;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 13-SEP-2023, entry version 30.
DE SubName: Full=3-isopropylmalate dehydrogenase {ECO:0000313|EMBL:KKT55137.1};
GN ORFNames=UW45_C0009G0009 {ECO:0000313|EMBL:KKT55137.1};
OS Parcubacteria group bacterium GW2011_GWC2_44_22.
OC Bacteria.
OX NCBI_TaxID=1618930 {ECO:0000313|EMBL:KKT55137.1, ECO:0000313|Proteomes:UP000034136};
RN [1] {ECO:0000313|EMBL:KKT55137.1, ECO:0000313|Proteomes:UP000034136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|RuleBase:RU004443}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKT55137.1}.
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DR EMBL; LCII01000009; KKT55137.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1KFS5; -.
DR PATRIC; fig|1618930.3.peg.402; -.
DR Proteomes; UP000034136; Unassembled WGS sequence.
DR GO; GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR InterPro; IPR004429; Isopropylmalate_DH.
DR NCBIfam; TIGR00169; leuB; 1.
DR PANTHER; PTHR42979; 3-ISOPROPYLMALATE DEHYDROGENASE; 1.
DR PANTHER; PTHR42979:SF1; 3-ISOPROPYLMALATE DEHYDROGENASE; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Branched-chain amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023304};
KW Leucine biosynthesis {ECO:0000256|ARBA:ARBA00022430};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU004443}.
FT DOMAIN 11..348
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 358 AA; 39374 MW; 493FEF903CB23960 CRC64;
MKTAENQKTY QIAVIGGDGI GPEITVEAVK VLEAVAKRLS CQFIFKHLLA GGEAWDKFGK
HLPEETVAVC QQSQAILFGA VGGPVEEATK EKWAGVERNV ILGLRSEFDL FANIRPIKGE
GADFVIVREL TSDIYFGNVK ARHLIKFDEL SSEETVDVMY YNTSEIERIL EVAFKLAGTR
KRQVTLVDKA NVLETSKLWR RVAERLVMKY PDIQLKYMFV DNAAYQIAKN PDQFDVLVTG
NMFGDILSDE AAVWAKSLGM IPSGSWGGSS FGMYEPAHGS APKHTGLGTA NPLATILSAA
MLLRHSLKLL DGAFMIEQAV EKVLQQGYGT PDLQPEKVVT TKEIGDLVVK QIIPKGIN
//
