ID   A0A0G1N5T4_9BACT        Unreviewed;       307 AA.
AC   A0A0G1N5T4;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Nucleotide sugar dehydrogenase {ECO:0000313|EMBL:KKU15966.1};
GN   ORFNames=UX25_C0049G0002 {ECO:0000313|EMBL:KKU15966.1};
OS   Candidatus Woesebacteria bacterium GW2011_GWC2_45_9.
OC   Bacteria; Candidatus Woesebacteria.
OX   NCBI_TaxID=1618589 {ECO:0000313|EMBL:KKU15966.1, ECO:0000313|Proteomes:UP000034922};
RN   [1] {ECO:0000313|EMBL:KKU15966.1, ECO:0000313|Proteomes:UP000034922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT   radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00006601}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKU15966.1}.
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DR   EMBL; LCLM01000049; KKU15966.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G1N5T4; -.
DR   STRING; 1618589.UX25_C0049G0002; -.
DR   Proteomes; UP000034922; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR   InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR   PANTHER; PTHR43750; UDP-GLUCOSE 6-DEHYDROGENASE TUAD; 1.
DR   PANTHER; PTHR43750:SF3; UDP-GLUCOSE 6-DEHYDROGENASE TUAD; 1.
DR   Pfam; PF00984; UDPG_MGDP_dh; 1.
DR   Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
FT   DOMAIN          63..163
FT                   /note="UDP-glucose/GDP-mannose dehydrogenase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03721"
FT   DOMAIN          190..282
FT                   /note="UDP-glucose/GDP-mannose dehydrogenase dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF00984"
SQ   SEQUENCE   307 AA;  33973 MW;  0BFFD1D0CD7058E8 CRC64;
     MVEMSGWLTP RLSGEPSCDN LAPCMAKIGI IGWGVVGQAV GKGFETKGHQ IFWYSRKPGP
     YSLNQVINKS EFIFLCLPTP MFSDYSGIDL SIIDEVVSRV APKISGTDKI LIIKSTVIPG
     TTASYKKKYP KVYLAMNPEF LTEANALGDF LKPDRTVIGA FSQSVWGKLS SLYQDLYGAN
     SKIFLTDPTT AEMVKYMSNA LLATKVIFAN EMYDLCSALG IKYEEVKDMV AVDPRIGPSH
     LSVTTIRGFG GKCFPKDMVA LIGFAKDKKV DASLLKTVWE KNLRIRKIRD WEEISGAVNK
     KSKKKSH
//