ID   A0A0G1Q2W3_9BACT        Unreviewed;       824 AA.
AC   A0A0G1Q2W3;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=UX55_C0037G0003 {ECO:0000313|EMBL:KKU39411.1};
OS   Candidatus Azambacteria bacterium GW2011_GWE2_46_45.
OC   Bacteria; Candidatus Azambacteria.
OX   NCBI_TaxID=1618625 {ECO:0000313|EMBL:KKU39411.1, ECO:0000313|Proteomes:UP000034202};
RN   [1] {ECO:0000313|EMBL:KKU39411.1, ECO:0000313|Proteomes:UP000034202}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT   radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKU39411.1}.
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DR   EMBL; LCMQ01000037; KKU39411.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G1Q2W3; -.
DR   PATRIC; fig|1618625.3.peg.484; -.
DR   Proteomes; UP000034202; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003916; F:DNA topoisomerase activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   Gene3D; 3.30.65.10; Bacterial Topoisomerase I, domain 1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013498; Topo_IA_Znf.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF63; DNA HELICASE IV; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   Pfam; PF01396; zf-C4_Topoisom; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}.
FT   DOMAIN          133..597
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         154..161
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   824 AA;  95602 MW;  89B145DCCA346AC3 CRC64;
     MGFVIIAVII LIFATYKLSE ALKNKRSLAL LLSLKKYEPD FKNALIDFQS LAQGNWYISD
     RQYRLWKDKY EYLAGMLNPV FYKIKNKNPF KKLVMDFAGF WYEGRKLFID GFNEKFVKQE
     SSVIKRILSE KEIQNNNDQV TAIASDEDNT LLVAGAGTGK TTTILGKLAY LIERVGVKPE
     DILLLSFTGR AVEELTDRIS KKFSDKNIKA LTFHSFGLSI IGKVLGQKPD LAFSTGAGRQ
     KFLNEQFDML LKNSDYLHRA VEYFAYYFKP VVLEPGFKNF DDYYKYVKTE QNLTLQKERV
     KSQQEVMIAN FLYINGINYV YEQPYKHPTS TSEYRQYKPD FYLADYDIYL EHFGINRNGE
     VRFTQNVAQN AVRTKKYQAE MAWKRDLHKK HQTILVETFS YEFTERNWME RLTSKLQAHN
     VNFSKRNIGE IFSTLKASGS VKQIVELFGT FLDLSKSNGY TLPKLQSIIL SRNSTRELAF
     FDIFSPIYQA YEKYLDRTNS IDFHDMLIKA ANFINEGQFK TNFKYIIIDE FQDFSKSKYL
     LVKALCEQNP GVKLFCVGDD WQSIFRFAGS DISLMTNFEE DYGFTRKNQL IITNRFNNQL
     AVVSNQFILK NPHQIKKEVR SEKTVFGEAV EILHKRNTND TEQLLREILS SLNKTAAGER
     KIATVFLLGR YKHNKPGDFL KYQNQYKKLS IEFLTIHASK GTEADYVIIM DVLAGKYGFP
     SEVTDDPLLE IVLSKGDSYP HAEERRLMYV AMTRARHKVF IITEDGRQSV FVLELEGSKN
     PNTTTMRCED CGGEMVKRKG PYGTFYGCIN YPKCDFKVNI RRAH
//