ID A0A0G1QJF4_9BACT Unreviewed; 300 AA.
AC A0A0G1QJF4;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=thymidylate synthase {ECO:0000256|ARBA:ARBA00011947};
DE EC=2.1.1.45 {ECO:0000256|ARBA:ARBA00011947};
GN ORFNames=UX28_C0003G0096 {ECO:0000313|EMBL:KKU17918.1};
OS Candidatus Pacebacteria bacterium GW2011_GWA1_46_10.
OC Bacteria; Candidatus Paceibacterota.
OX NCBI_TaxID=1618469 {ECO:0000313|EMBL:KKU17918.1, ECO:0000313|Proteomes:UP000034432};
RN [1] {ECO:0000313|EMBL:KKU17918.1, ECO:0000313|Proteomes:UP000034432}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKU17918.1}.
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DR EMBL; LCLP01000003; KKU17918.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1QJF4; -.
DR STRING; 1618469.UX28_C0003G0096; -.
DR Proteomes; UP000034432; Unassembled WGS sequence.
DR GO; GO:0004799; F:thymidylate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd00351; TS_Pyrimidine_HMase; 1.
DR Gene3D; 3.30.572.10; Thymidylate synthase/dCMP hydroxymethylase domain; 1.
DR InterPro; IPR045097; Thymidate_synth/dCMP_Mease.
DR InterPro; IPR023451; Thymidate_synth/dCMP_Mease_dom.
DR InterPro; IPR036926; Thymidate_synth/dCMP_Mease_sf.
DR InterPro; IPR000398; Thymidylate_synthase.
DR NCBIfam; TIGR03284; thym_sym; 1.
DR PANTHER; PTHR11548; THYMIDYLATE SYNTHASE 1; 1.
DR PANTHER; PTHR11548:SF1; THYMIDYLATE SYNTHASE-RELATED; 1.
DR Pfam; PF00303; Thymidylat_synt; 1.
DR PRINTS; PR00108; THYMDSNTHASE.
DR SUPFAM; SSF55831; Thymidylate synthase/dCMP hydroxymethylase; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 14..293
FT /note="Thymidylate synthase/dCMP hydroxymethylase"
FT /evidence="ECO:0000259|Pfam:PF00303"
SQ SEQUENCE 300 AA; 34574 MW; F28DBCFBAF957B41 CRC64;
MLEHLPINQR TPDHQYKDLL REILEKGVRT GTQLETDALT LIGPKPMHFK LANGFPMITE
RKISEKMWTQ AIGEIFAFIN GARTLKQLEE FGCYWWAPWG VERKTKKRGL APGDLGPGSY
GAAFHDFPTS EGPTHNQFKD IIEEMKVLPH LRTHFITPWV PQYIARRKRK GKTQKVVVCP
CHGWIHFRIL DGKLTLHMFQ RSGDVPVGVP ANMVQYAALL IAVAQVLGVE PYEYVHTISD
AHIYVDQISR VEEMLKREDR AFPTMTLKKK HQDIFQYRAT DFELSDYDPH PGIWDFPVSV
//
