ID A0A0G1U8P9_9BACT Unreviewed; 809 AA.
AC A0A0G1U8P9;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=UY19_C0002G0065 {ECO:0000313|EMBL:KKU90492.1};
OS Candidatus Wolfebacteria bacterium GW2011_GWA2_47_9b.
OC Bacteria; Candidatus Wolfebacteria.
OX NCBI_TaxID=1619005 {ECO:0000313|EMBL:KKU90492.1, ECO:0000313|Proteomes:UP000033882};
RN [1] {ECO:0000313|EMBL:KKU90492.1, ECO:0000313|Proteomes:UP000033882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKU90492.1}.
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DR EMBL; LCPB01000002; KKU90492.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1U8P9; -.
DR Proteomes; UP000033882; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR45528; SENSOR HISTIDINE KINASE CPXA; 1.
DR PANTHER; PTHR45528:SF9; SENSOR HISTIDINE KINASE YRKQ; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KKU90492.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 332..384
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 435..489
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 570..796
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 376..431
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 809 AA; 89280 MW; F0A902C94E0BC990 CRC64;
MHKQISLRNK ITAFTVGSIL LFGSVAIAIV FFYARSNYYA LRQADIRTEV LEQASDIGAS
LEQAKRIVKH IASEKELIRY LEGDAESSDR ARIVDMLSHY NGERLYDPLY VLDRSGIATA
SLDSTFVGND YSFRSYFTNA MRGESTAEFL IGVTSGKAGY YFSSPVISSD GGIIGVVVGK
VSRDIGNELI SGSFLIENGS IMITDTDGIV LYASRADQLY HSIGVLSDED RDRITGNRQF
ANLPLTSLGY NRIFQAIRTH TGTPDLFDFS NPVTHENEVV AVVAIPQTDL FLVVQESVVS
LIAPVRIILF GLIIAVLLSM LATSIFVYVL VRQFLAPLSR LKFAAERISA GAFDYRVEIK
TGDELGKMGE QFNVMADRLK NSYAGLERTV AEKTSELSAK LVSIEQKNAE LRDTQRAVLN
ILEDARSLEA QIADERNHLR GILAAMGEGL FVLDDRYRIV LSNPIAERIL DMQADEIIGK
SMSDIITLYK GKEEVPVEGR PMVKVFTEGK IIAADLRDDF YWQTSKGRKF PVGFIAAPLT
VGGIRNEVVV FRNLEKEKNL DEARTSFISI TSHQLRTPLT SIKWFLEMLM EGSYADPLTV
KQREFADLAY QASEKMVGII NLLLQIARVE SGRLKVLPVP TDLKQLTASI IASFGNAFQM
RKQVIIVQTV PDPLPVIQID VDVMGQVIQN LLSNANRYAN ENSTIIISIE AGQGEQGSDF
ITYSIADQGI GIGKNATSRI FEKFYRAENA LRSVPEGSGL GLSLVKSLVE GWGGRVWFES
EEGKGTTFFF TIPIGGMQAR AGEVGIAVT
//
