ID A0A0G1W0H2_9BACT Unreviewed; 457 AA.
AC A0A0G1W0H2;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=D-alanyl-D-alanine carboxypeptidase {ECO:0000313|EMBL:KKU75805.1};
DE Flags: Fragment;
GN ORFNames=UY01_C0004G0032 {ECO:0000313|EMBL:KKU75805.1};
OS Candidatus Nomurabacteria bacterium GW2011_GWB1_47_6.
OC Bacteria; Candidatus Nomurabacteria.
OX NCBI_TaxID=1618749 {ECO:0000313|EMBL:KKU75805.1, ECO:0000313|Proteomes:UP000034879};
RN [1] {ECO:0000313|EMBL:KKU75805.1, ECO:0000313|Proteomes:UP000034879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- SIMILARITY: Belongs to the CapA family.
CC {ECO:0000256|ARBA:ARBA00005662}.
CC -!- SIMILARITY: Belongs to the peptidase S11 family.
CC {ECO:0000256|ARBA:ARBA00007164, ECO:0000256|RuleBase:RU004016}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKU75805.1}.
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DR EMBL; LCOJ01000004; KKU75805.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1W0H2; -.
DR Proteomes; UP000034879; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR019079; Capsule_synth_CapA.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR018044; Peptidase_S11.
DR InterPro; IPR001967; Peptidase_S11_N.
DR PANTHER; PTHR33393; POLYGLUTAMINE SYNTHESIS ACCESSORY PROTEIN RV0574C-RELATED; 1.
DR PANTHER; PTHR33393:SF11; POLYGLUTAMINE SYNTHESIS ACCESSORY PROTEIN RV0574C-RELATED; 1.
DR Pfam; PF00768; Peptidase_S11; 1.
DR Pfam; PF09587; PGA_cap; 1.
DR PRINTS; PR00725; DADACBPTASE1.
DR SMART; SM00854; PGA_cap; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 3: Inferred from homology;
KW Carboxypeptidase {ECO:0000313|EMBL:KKU75805.1};
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984};
KW Protease {ECO:0000313|EMBL:KKU75805.1};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 338..457
FT /note="Capsule synthesis protein CapA"
FT /evidence="ECO:0000259|SMART:SM00854"
FT ACT_SITE 104
FT /note="Acyl-ester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR618044-1"
FT ACT_SITE 107
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR618044-1"
FT ACT_SITE 159
FT /evidence="ECO:0000256|PIRSR:PIRSR618044-1"
FT BINDING 257
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR618044-2"
FT NON_TER 457
FT /evidence="ECO:0000313|EMBL:KKU75805.1"
SQ SEQUENCE 457 AA; 49760 MW; 761B53FBFD44F033 CRC64;
MKFVRKNKRI IVWAAFPVAF GVLVSSFLFS FLKIGNALEN TKNVLFAVSM APEENQSEKP
QYFYINKSEG TKPKVSAQAF LVGDLKTGEV ILSKNQETKF PMASVSKLMT ALVTSELAKS
EDVATVSKKA IATLGQNGEL RAGEKIKAAD LVYPLLLESS NDAAEALAEH FGRQNFMDKM
NLQAEQLMMS STSYEDPSGL SPNNKSTAAD LFKLAGYIEE KHGELFDITA KRSYSAPKHN
WSNISQFLGK DGYSGGKSGY TDAALQSGVA IFELPLGESG TRPIAITLLR SLDRKKDVEN
ILKYLGSYVY YGGKTDSARA WVEEKVGMPP IYEPSFVTLS FLGDIMLDRG VRGSVVKNFK
NDYSALFVKI PQKLLKNSDI AFANLEGTAS DQGVDGKNLY SFRMDPGVIP ALAGAGLDIL
SVGNNHVGDW GRSAYADTLS RLKENEILYT GGGMGEA
//
