ID A0A0G1YY40_9BACT Unreviewed; 869 AA.
AC A0A0G1YY40;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE RecName: Full=Toprim domain-containing protein {ECO:0000259|PROSITE:PS50880};
GN ORFNames=UY99_C0002G0002 {ECO:0000313|EMBL:KKW48398.1};
OS Parcubacteria group bacterium GW2011_GWA1_59_11.
OC Bacteria.
OX NCBI_TaxID=1618804 {ECO:0000313|EMBL:KKW48398.1, ECO:0000313|Proteomes:UP000033896};
RN [1] {ECO:0000313|EMBL:KKW48398.1, ECO:0000313|Proteomes:UP000033896}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKW48398.1}.
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DR EMBL; LCSE01000002; KKW48398.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1YY40; -.
DR Proteomes; UP000033896; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-KW.
DR CDD; cd01029; TOPRIM_primases; 1.
DR Gene3D; 3.40.1360.10; -; 1.
DR Gene3D; 3.90.580.10; Zinc finger, CHC2-type domain; 1.
DR InterPro; IPR036977; DNA_primase_Znf_CHC2.
DR InterPro; IPR034154; TOPRIM_DnaG/twinkle.
DR InterPro; IPR006171; TOPRIM_domain.
DR Pfam; PF13155; Toprim_2; 1.
DR SMART; SM00493; TOPRIM; 1.
DR SUPFAM; SSF56731; DNA primase core; 1.
DR PROSITE; PS50880; TOPRIM; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Primosome {ECO:0000256|ARBA:ARBA00022515};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 761..844
FT /note="Toprim"
FT /evidence="ECO:0000259|PROSITE:PS50880"
SQ SEQUENCE 869 AA; 95980 MW; 32B8B306F9C58BD3 CRC64;
MADVFPVTPE DLSEMTMPAP FGDWAWEMML GGKIDLFVQA LVQSGEVSSK PEALARLSEL
SRRFEVKNGH VSWGDLANDG FHYALFSELE NLLGVKRARH AEPFLSCGVL GHKLMAQLFA
REEPFGNGWA DLEQMTLFSE ERSLPLFESA VPVSHLRSRR FSTDRALARV DAVWAELCGR
IAGTGNWADW YQVSRREVAE LYASMAPFLG EYLAELNRKP GVAGGYVAAL SVMTWVTALH
LYLEAGPRPY FPELRLFDPS IHGLGGGRLD ALEVTGVRGK PPTASQKRML RQMSRHRFGS
LTELLRDLLT LFGAGAEVNI RDWKFAIGDG PHKLIVPEDV AQAPFPKHAE QMRRYLTFAS
VSNHLAGAGE LWNADSGAKQ ADLIYLLPTV ESIEHRVGMA PSDKERAFLE WVVKRWGSAE
RRSSVRHLNG ALGRYLVRLL SGKTDGRKKA TVQPLLMETD LNGGGKVVSL VDRHRFLDEN
RIIERRPEGR LFLHLDHLIQ AIESGRLDVG RGFNLDRGGL IRCPMPGHAD PGRPSCSVRL
DQGSFHCFGC NASGWFDPRS VPPDFDIDWS AARRVGGSAA MFPEPFVPSE HHGFMSLVQE
LLRSEFGGGA GARYLREERG LDPDLAREHG AGFGGDVLIH GLLDAGRDVD ELIQYGILGL
SSNMLPDYRL PRLLARRGFG PDDLRRPIPS ARRNAEPVYG LPYSVLEGRV TFPLTYDGKI
TNFYGRSIRK DSPVPHRKLS TAATGVLHGG FNMEILRGDG RELFVAEAVI DALTLIETGR
PSLALIGVDN SAILRETAKE LAAHPKEVVL VLDADEAGQK ASERVAVKLR SFGFNGSVRN
GTAEVVPPGF DDVNKWWVEA GRMIWSGAQ
//
