ID A0A0G2AMU8_9BACT Unreviewed; 368 AA.
AC A0A0G2AMU8;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Membrane-associated zinc metalloprotease {ECO:0000313|EMBL:KKW34009.1};
GN ORFNames=UY79_C0007G0029 {ECO:0000313|EMBL:KKW34009.1};
OS Parcubacteria group bacterium GW2011_GWA2_53_21.
OC Bacteria.
OX NCBI_TaxID=1618858 {ECO:0000313|EMBL:KKW34009.1, ECO:0000313|Proteomes:UP000033913};
RN [1] {ECO:0000313|EMBL:KKW34009.1, ECO:0000313|Proteomes:UP000033913}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase M50B family.
CC {ECO:0000256|ARBA:ARBA00007931}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKW34009.1}.
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DR EMBL; LCRK01000007; KKW34009.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G2AMU8; -.
DR Proteomes; UP000033913; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR CDD; cd06163; S2P-M50_PDZ_RseP-like; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR004387; Pept_M50_Zn.
DR InterPro; IPR008915; Peptidase_M50.
DR PANTHER; PTHR42837:SF2; MEMBRANE METALLOPROTEASE ARASP2, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR42837; REGULATOR OF SIGMA-E PROTEASE RSEP; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF02163; Peptidase_M50; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000313|EMBL:KKW34009.1};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:KKW34009.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 109..191
FT /note="PDZ"
FT /evidence="ECO:0000259|SMART:SM00228"
SQ SEQUENCE 368 AA; 39723 MW; BFC480073E7555DA CRC64;
MIGTIILFLV LLSLLVFVHE LGHFWMARRA GMKVDEFGFG FPPRLFGIKR KGTTYSINWI
PLGGFVKIKG ESGSHTDESD SFAAKSAWRR FLVLIAGVGM NVVLAAALFG IGFMVGLPSV
ILDDVSARAH VRDEAIRIVQ VLTDSPAEAA GLKLGDVVVS VDDQLFSGVE PLYDYLGAQE
DPMEFLLRRG DGFVTQTVSR GAINGYEGDL LGIQIVRTGF VSYSFFEAIG RGVVTSVTMT
GAVVVAFVDL IRDLIVTSSV SVDVSGPVGI AVMTGEVADL GFSYLLQFAA ILSINLAVIN
ALPFPALDGG RILFLAIEKL RRKKMSERVE ALTHNLGFLV LIGLVVLVTY RDLVRFGDEI
LGAVKSVF
//
