ID A0A0G2BCF4_9BACT Unreviewed; 700 AA.
AC A0A0G2BCF4;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 03-MAY-2023, entry version 30.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=UY93_C0003G0027 {ECO:0000313|EMBL:KKW43244.1};
OS Parcubacteria group bacterium GW2011_GWA1_56_13.
OC Bacteria.
OX NCBI_TaxID=1618803 {ECO:0000313|EMBL:KKW43244.1, ECO:0000313|Proteomes:UP000034801};
RN [1] {ECO:0000313|EMBL:KKW43244.1, ECO:0000313|Proteomes:UP000034801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKW43244.1}.
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DR EMBL; LCRY01000003; KKW43244.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G2BCF4; -.
DR STRING; 1618803.UY93_C0003G0027; -.
DR Proteomes; UP000034801; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17580; REC_2_DhkD-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR007895; MASE1.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF05231; MASE1; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000313|EMBL:KKW43244.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000313|EMBL:KKW43244.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 330..548
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 578..692
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 548..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 627
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 700 AA; 77008 MW; 8D4ECE85CABFCFBD CRC64;
MGILSVSFPL EMAKPLQRDT DTKQTNLFVF IFFAYLVTGY VGLHIHAVNT FAALVWPPSG
IAFAAFILYG YRVWPGVFFA AFLLNSSVGA APLVALAIAL GNTLGPLAGS FLIRWYTNYT
PSVIRLRDNV GIVANAFLIS GVTATVGTGA LWLGGSVSSV AFSATWGTWW IGDTLGILVC
TPFILKWFNQ PLYKRTRLQY VELAASSAAV AVFSYMIFWS SYTSFAYGLF IPLTWVALRT
GPRGMTLSLL IASVIAIPGT ILGHGPFVDL GLWHLQVFLA TMSVVFLVFT AVVEERKEAL
KTLAQHVDEL ETALYKISSE DEAKKEFLAV LAHELRNPLA TVLNSIELIR MQGISTPNAS
KLLETINERA RAMVRLLDDL LDISRISQKK LSLHKEAINL DEFINRLEQS ILPFAQKHGH
ALTITRSDEE LLVEADPVRL EQIFVNLVTN AVKFTKKPSG LIDLAVRREK DTAVISVRDN
GMGIPKNMLR RIFEPFFQIN RGQLSSEGVG IGLPLTRQLV EMHGGTIEAK SAGLNTGSEF
IVRLPLSKAA RPKPPSPDDI PLSPQTVHRS RRVKRAFKIL VVDDNAEATD ALAKLLELRG
HATTIAYTGA EAVQKALEFE PEIVLLDIGL PDIDGYEVAR QLHAQKKPYF LIALTGYGQD
EDKERARQAG IDYHLTKPAG LKEIAAALKR VPHPFGVRGV
//
