ID A0A0G2BIK1_9BACT Unreviewed; 400 AA.
AC A0A0G2BIK1;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=tyrosine--tRNA ligase {ECO:0000256|ARBA:ARBA00013160};
DE EC=6.1.1.1 {ECO:0000256|ARBA:ARBA00013160};
DE AltName: Full=Tyrosyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00033323};
GN ORFNames=UY96_C0019G0015 {ECO:0000313|EMBL:KKW45549.1};
OS Parcubacteria group bacterium GW2011_GWB1_56_8.
OC Bacteria.
OX NCBI_TaxID=1618888 {ECO:0000313|EMBL:KKW45549.1, ECO:0000313|Proteomes:UP000034284};
RN [1] {ECO:0000313|EMBL:KKW45549.1, ECO:0000313|Proteomes:UP000034284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-
CC tyrosyl-tRNA(Tyr); Xref=Rhea:RHEA:10220, Rhea:RHEA-COMP:9706,
CC Rhea:RHEA-COMP:9707, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:58315, ChEBI:CHEBI:78442,
CC ChEBI:CHEBI:78536, ChEBI:CHEBI:456215; EC=6.1.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000069};
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC {ECO:0000256|RuleBase:RU363036}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKW45549.1}.
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DR EMBL; LCSB01000019; KKW45549.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G2BIK1; -.
DR PATRIC; fig|1618888.3.peg.709; -.
DR Proteomes; UP000034284; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004831; F:tyrosine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006437; P:tyrosyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00805; TyrRS_core; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR Gene3D; 1.10.240.10; Tyrosyl-Transfer RNA Synthetase; 1.
DR InterPro; IPR002305; aa-tRNA-synth_Ic.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR InterPro; IPR002307; Tyr-tRNA-ligase.
DR InterPro; IPR024088; Tyr-tRNA-ligase_bac-type.
DR NCBIfam; TIGR00234; tyrS; 1.
DR PANTHER; PTHR11766:SF1; TYROSINE--TRNA LIGASE; 1.
DR PANTHER; PTHR11766; TYROSYL-TRNA SYNTHETASE; 1.
DR Pfam; PF00579; tRNA-synt_1b; 1.
DR PRINTS; PR01040; TRNASYNTHTYR.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000256|RuleBase:RU363036};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363036};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363036};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363036};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW ECO:0000256|RuleBase:RU363036};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182}.
SQ SEQUENCE 400 AA; 45208 MW; 3BBCB56EA326A00B CRC64;
MARTGLKDAG KIRHLLARNV EQVIDRAHLE KTLKSGKKLR IKLGIDPTGE KIHIGRAIVL
WKLREFQELG HQVVLIIGDF TAQIGDPSDK LSKRPMLSRE QVEKNMRDYL SQIGKILDLH
KTETRYNSKW LDKLNFRETA ELAESFSVQQ MLHRRNFQER WKEGQDISLR EFLYPIIQGY
DSVAIKADVE LGGTDQLFNL MAGREVQKQC GQKPQDVMTV GMLSGTDGRK MSTSWGNVIN
IVDPADEQFG KIMSMHDKMI QDYFHMATRM PEKEIAEQDR ALARGANPRD VKLVLAKEIV
ALYHGKPAAE KAAEKWVKMF SKKDVSGADI PTLKLKNKKI AAVDLVLKSG AATSKGEAWR
LIAQGGLKAG EKTISNPRQE LNLKGGEVVR VGKKRFFRIN
//
