ID A0A0G2HJI3_9PEZI Unreviewed; 2096 AA.
AC A0A0G2HJI3;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Putative polyketide synthase {ECO:0000313|EMBL:KKY35203.1};
GN ORFNames=UCDDA912_g04810 {ECO:0000313|EMBL:KKY35203.1};
OS Diaporthe ampelina.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Diaporthales; Diaporthaceae; Diaporthe.
OX NCBI_TaxID=1214573 {ECO:0000313|EMBL:KKY35203.1, ECO:0000313|Proteomes:UP000034680};
RN [1] {ECO:0000313|EMBL:KKY35203.1, ECO:0000313|Proteomes:UP000034680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DA912 {ECO:0000313|EMBL:KKY35203.1};
RA Lawrence D.P., Travadon R., Rolshausen P.E., Baumgartner K.;
RT "Distinctive expansion of gene families associated with plant cell wall
RT degradation and secondary metabolism in the genomes of grapevine trunk
RT pathogens.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KKY35203.1, ECO:0000313|Proteomes:UP000034680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DA912 {ECO:0000313|EMBL:KKY35203.1};
RA Morales-Cruz A., Amrine K.C., Cantu D.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKY35203.1}.
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DR EMBL; LCUC01000169; KKY35203.1; -; Genomic_DNA.
DR STRING; 1214573.A0A0G2HJI3; -.
DR OrthoDB; 5396558at2759; -.
DR Proteomes; UP000034680; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd05195; enoyl_red; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.70.250; Malonyl-CoA ACP transacylase, ACP-binding; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020807; PKS_DH.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43775:SF29; ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED; 1.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR Pfam; PF08659; KR; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR Pfam; PF21089; PKS_DH_N; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF14765; PS-DH; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00826; PKS_DH; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SMART; SM00822; PKS_KR; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50075; CARRIER; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000034680};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 2017..2094
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2096 AA; 232440 MW; 79133508EF7CF4B2 CRC64;
MAIDWITKGF THRTHHPWRT FGVVDQFRVS DLAVGETLSP AVRAGHIAPL LHFLFTGQGA
QWPRMGLELL QFEPFHRALE QADSFLRQEL GCEWSLVHQL ELSAGSKIGQ PALAQPLTTA
LQVALVDLMR SWNIVPTSVT GHSSGEIAAA YCAGVLSREE AWTIAYFRGV VSERLASNTK
LPKSGMMSVG LGAETAQTYL DEEGVADRVT VACVNSPINV TISGHVDALN IIYHRLEKDE
LFVRRLDVQV AYHNPRIMSE VAEEYGRMLS KALDGSPSKG HDTAISFFSS VTAGRLSDME
ELRQPAYWVR NLISTVRFAD AIGSAVQESA AVKATRNSSH YFVEIGPQAA LRRPVQDTLK
VLSKDKYQYT NTLDAKKDSV ACLLGAIGQL WCTGMDIDLA RVNRSCFVTS AALEGKASTD
EPRVLADLPS YPFSRARLDW AESRLSSGFA FRPHRRHGLL GLPARDWNPN EASWRHIIRH
AENPWILDHT VNGSSVYPGA GIIVMAIEAA RQMTEGQQQK ENQNKQQRIV GYRVADVRFL
RSIAVDSGER GSEAQLHMRQ RRDNINNTLQ KWYDWRVFTI GSADEWLEAA HGSIKVEVET
IGSADEASHR RQQREAEKLR AEHDRIIDSC KFKTYPDQMY GNIRAHGMDY GPYFARLSDI
SYDNNGRAAA SVTTRDYAEK MEYANEDPCV IHPTTLDALC HLQMVSVSAG GLRSMPAMMF
THCREMWVSN RLFELPGNLR LQVATTETMR GFRECECDTV ALLAETREPV VIIRGERGTA
ITSLDHDASE AEPIAACYQL AYHADLSLMT NDESHKFLMN NTFRDFALPD KNCLDRVDAL
VRYFVDKTLG RLEKEGFPNP TDHLAEYVKW MKRVRQGPDK HIQESYGSAD IDVEALLLKQ
AAEPTEQLVR RVGQNLHDIL TGQANALQIL FEDTLMQEYY SAEVFQIHCD RVGAYVEILA
HANPYLRILE VGAGTGSSAA GVLPYLTYYQ GDGKKTPRIA EYMYTDISPG FFEKAQERFA
DYASVMKYKK LDLEEDPIPQ GFEEGSYDVV IAGNVLHATS DLAQSLRSVR RLLKPGGKFI
MVEITNPQSA RENFIFGLLS GWWLRALSGG SSNWVYPNQG PLLTDEQWND ALKETGFSGT
DLQLKDHDKP PYHRLSTLVA TAVKPASAVE ERRQRTTHII KKDGSELQTR LAEAIKSQLT
DHSVTVTNLG EISTVDLTGV NTISVLEAND SILHDPDEDQ MSAIKHYAME SQRMIWVTSG
GGPQARRPEA DISLGFARTV CTERGDQGVI VMSLESPEDA NHSARLITAV LRRAAEDDEE
ESWRESELAE VGGVLQIPRV APNGRLNDVI TSRTHTPKMQ TCAIGPEVQQ HISLSIKNPG
LLDTLYFKEV AGAGAALGDG EVEIQVMASS MNFKDVMIAL GQIPSHGFGY DGAGIITRTG
PNCRYTKPGD RVMFVSMTGA FSTFVRVSEL LTQAMLDGMS FTIAASIPVI YSTVVFSLNY
IARIQPGESI LIHSAAGGVG QVAIMVAKKR GVEDIYVTVS NETKRKLLVD MYGIRPENIF
YSRDTSFVDD IMHATGGRGV DVVLNSLGGE LLQQSWKCIK TFGRFVEIGK ADILQKTGLT
MEPFERNATF SAVDMYVVVE NAQETMKQVM TDVMDLWSKY PDEVHEPRPL HVYPAAKFED
AMRYLQSGKN IGKTVIDWSR PAQVPYRPML QPAYRFRADA SYVLAGGLGG LSREIVHWMM
GRGARNFICL SRSGVQGNRE AQKFIQEVEK SGATIIAPAC NIAHRESLEK TLRDCLSKVP
PIKGCIQGAM VLHDELMANM TAKVWKEPLD PKYHGSLNLH ELLPQDLDFC IFLSSFAGVN
GNGGQSNYAA GNTYQGSLAR HRIQRGLRGI TVDLGLILEA GLANSNHFFV QSALRAGFTG
VTQDQFLGLL DAVCDQAYDY SQPGAAEVIH VVDSPKQLWE KGDQSTVAWM SKPLFRNLHR
LGATYDSSAD AAGGNGLTRE DEVDYLSKVS AAASEEEAAE IITRGLIQKL SKSLSLPEAD
LDPSKPAFRL GVDSLIAVEV RYWFMKQLRV EVSVLNILKD QSLTELCYSV VGEILK
//
