ID A0A0G2HU08_9EURO Unreviewed; 870 AA.
AC A0A0G2HU08;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Potassium transport protein {ECO:0000256|PIRNR:PIRNR002450};
GN ORFNames=EMCG_04175 {ECO:0000313|EMBL:KKZ61220.1};
OS Emmonsia crescens UAMH 3008.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emmonsia.
OX NCBI_TaxID=1247875 {ECO:0000313|EMBL:KKZ61220.1, ECO:0000313|Proteomes:UP000034164};
RN [1] {ECO:0000313|Proteomes:UP000034164}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 3008 {ECO:0000313|Proteomes:UP000034164};
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TrkH potassium transport family.
CC {ECO:0000256|ARBA:ARBA00009137, ECO:0000256|PIRNR:PIRNR002450}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKZ61220.1}.
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DR EMBL; LCZI01001328; KKZ61220.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G2HU08; -.
DR VEuPathDB; FungiDB:EMCG_04175; -.
DR Proteomes; UP000034164; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0030007; P:intracellular potassium ion homeostasis; IEA:UniProtKB-UniRule.
DR InterPro; IPR003445; Cat_transpt.
DR InterPro; IPR004773; K/Na_transp_Trk/HKT.
DR InterPro; IPR015958; Trk_fungi.
DR NCBIfam; TIGR00934; 2a38euk; 1.
DR PANTHER; PTHR31064:SF30; HIGH-AFFINITY POTASSIUM TRANSPORT PROTEIN-RELATED; 1.
DR PANTHER; PTHR31064; POTASSIUM TRANSPORT PROTEIN DDB_G0292412-RELATED; 1.
DR Pfam; PF02386; TrkH; 1.
DR PIRSF; PIRSF002450; K+_transpter_TRK; 2.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002450};
KW Potassium {ECO:0000256|ARBA:ARBA00022958, ECO:0000256|PIRNR:PIRNR002450};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002450}.
FT TRANSMEM 43..65
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 104..127
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 434..459
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 500..518
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 569..589
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 634..651
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 698..714
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 726..746
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT REGION 153..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 809..870
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..222
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 809..841
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 870 AA; 97299 MW; 5DE11DC6C1CF66D8 CRC64;
MACQYGLRKV RLAYRSSLEG LMNALQVLNS IRARIPVISS IRLNFISIHY AYIICCALAC
SVVLYPTGNM QYIDALLFGA GSATQSGLNP IDINLLFTYQ QVGLWFVSMI TNPIIIHSFV
VFMRLFWFEK RFQHVVREAK TLRRFKSRQM TIPREEGVGN ERDPGREEMG VRGRKIVLLR
DTDTEQARGG LAVPDAVKKP DPETTSESDN SPKSTPDGRA SAQGEGQTGA KDRGDAANVK
ESPVAVDNDK NRELGTPQYL SPEHHITFLE NQRKQTGALR IPSPREYDRG GVPQTVDDTD
GGDLRQVQTS RSEEPTHSAP FAPLRRPSRG QHITIDEPDS ARMRSRTTTF PRVSSRRRPS
NTTSEHDTNF TPPERTRRGT LSSLFRSATT QDPDVDSSPY LSWQPTIGRN SAFVDLTEAQ
RNELGGIEYR ALKALAVVLI CYFFFFHLLG IICLVPWILE TERFGNVVRA AGQGRPWWAV
FTSGSAFNDQ GFALTPDSMI SFYDAVFPLL LLAFLIIIGN TGFPCMLRFV IWVFSHLVPH
GSPAWEELRF LLDHPRRCFT LLFPRTATWW LFGVLVILNG VDLFFFIILS LNDPEVNKIP
GGIRFVDGLF QAAATRTAGL SVINLAHLHP AVQVSYMIMM YISVFPIAIS VRRTNVYEEG
SLGIYSSPGA DDEEDETLGS KEFNYVGAHL RRQLSFDLWY IFLGLFVIAI VEAHRLETTS
ENSFSMFAVM FEIVSAYGTV GLSLGFPNTN TSLCAQFKPL SKLVIIAMEI RGRHRGLPYE
LDRAILLPSE SLNRKELLDA NKRSRRRGSV ASTFSGVARQ QSLSNPQWQE AGSSTAYQRD
GPPSSRWPEV TSPASGANPA PRLTTHHEVV
//
