ID A0A0G2HUY3_9EURO Unreviewed; 1166 AA.
AC A0A0G2HUY3;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
GN ORFNames=EMCG_00548 {ECO:0000313|EMBL:KKZ61565.1};
OS Emmonsia crescens UAMH 3008.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emmonsia.
OX NCBI_TaxID=1247875 {ECO:0000313|EMBL:KKZ61565.1, ECO:0000313|Proteomes:UP000034164};
RN [1] {ECO:0000313|Proteomes:UP000034164}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 3008 {ECO:0000313|Proteomes:UP000034164};
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKZ61565.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LCZI01001269; KKZ61565.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G2HUY3; -.
DR VEuPathDB; FungiDB:EMCG_00548; -.
DR Proteomes; UP000034164; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 3.40.50.1580; Nucleoside phosphorylase domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46082:SF11; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR46082; ATP/GTP-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF05729; NACHT; 1.
DR SMART; SM00248; ANK; 8.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53167; Purine and uridine phosphorylases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 7.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}.
FT DOMAIN 397..538
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REPEAT 852..885
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 889..918
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 922..954
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1015..1044
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1050..1077
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1078..1110
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1116..1143
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 1166 AA; 132947 MW; 93769A3A234686E9 CRC64;
MSTATNNMKL THDDYTVAWI CPLEVEQIAA MIMLDSEHER LPQPPNDHNV YTLGSINGHN
VVIAGLHSPG NNPAAVVVTQ MRNTFQQLRF GILVGIGGGV PTKTERGNIH LGHVVVSKPV
GEHSGVVQYD HGKAEVGQFR HTGYLAPPPT VLLNAAREMD VRRAMMLEDP LLNHIARIDT
VRQGLRRYKY PGAVNDHLYR AEYVHPNHSV SCRKCGCDLT QVVDRRAEDS DDDDDDDDVC
DEGPQLVVHR GTIAAGELVI KHGMLRDELA KQYGILCFEM EAAGALADFP CLVIRGISDY
SDSHKNDRWQ GYAAAAAAAY GRELFFHMPV DDVKQCKIAE HVDSLTQVNR YHQIFNWLKP
SDPSTNLNEA QERRQEGTGL WFLQSEPFKE WKSGTRRYLW LHGIPGCGKT VLSSTIIEHL
NQQLDSSHVV LNFFFDFTDT NKQSLDKLLR SLVAQLYSRC ENSRKALDKL FSSCEDGNRQ
PTYESLFATF LQMVNYVEKI QIIIDALDEC KTRRDLLSWM KNLTSSGHAG LHLLVTSRKE
EDIESELKRW LRLKDIVSIQ QDSVNHDIRA YVHERLRNDC HFKRWRSKPS VQDEIETELM
KKADGMFRWA ACQLDILQKC LDLRMLRESL RSIPKTLQET YARILASIDE NYRQYAIRIL
QFLTYSERPL NIQEAVDIIA VNLSEDPPFD SKQRMPEPRE IMNICSSLVS LVTREVSGET
FMELQLAHFS VQQYLKSEEI ETTFPEEMIK VGVIFQKGIN EISARGCITR ICLAYLSCLD
DQSSIEELKK RFPLAQYSAD YWMDHARPAE TKEDVQKSIL NFFLQQKQGY AVWRKYFDPD
NSFEREPRNW TKMATPLYYA SLAGLQHTVE LLLLEKGADV NVQGGRFCNA LQAAAMKDNK
KVVRLLLEKG ADINAQDDND GRYSNALHAA SALGHKEMVR LLLEAGANVN AKIMLFNRTI
HKIFIRDYRE KAKLDELHSN SLQAASFSKR GYEKVVRQLV LAEPDMSVKS NWYGNALQAA
SMMGHKEVMQ LLLEAGAKFN RQDEWYGFSL QTASFRGRKE VVQLLLEKGS DVNVKSKLYS
NALQAASMMG HKEVVQLLLE ARAKFNLQDE WYGFSLQTAS FRGRKEVVQL LLEAEADVNA
YSEQLSSFVS RYHTEMIQLL QDKEAH
//
