ID A0A0G2I4B5_9EURO Unreviewed; 370 AA.
AC A0A0G2I4B5;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=DNA-repair protein complementing XP-A cells {ECO:0000313|EMBL:KKZ65422.1};
GN ORFNames=EMCG_08756 {ECO:0000313|EMBL:KKZ65422.1};
OS Emmonsia crescens UAMH 3008.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emmonsia.
OX NCBI_TaxID=1247875 {ECO:0000313|EMBL:KKZ65422.1, ECO:0000313|Proteomes:UP000034164};
RN [1] {ECO:0000313|Proteomes:UP000034164}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 3008 {ECO:0000313|Proteomes:UP000034164};
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKZ65422.1}.
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DR EMBL; LCZI01000651; KKZ65422.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G2I4B5; -.
DR VEuPathDB; FungiDB:EMCG_08756; -.
DR Proteomes; UP000034164; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd21077; DBD_Rad14; 1.
DR Gene3D; 3.90.530.10; XPA C-terminal domain; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000465; XPA.
DR InterPro; IPR022656; XPA_C.
DR InterPro; IPR022658; XPA_CS.
DR InterPro; IPR037129; XPA_sf.
DR NCBIfam; TIGR00598; rad14; 1.
DR PANTHER; PTHR10142; DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS; 1.
DR PANTHER; PTHR10142:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS; 1.
DR Pfam; PF05181; XPA_C; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS00753; XPA_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 212..262
FT /note="XPA C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05181"
FT REGION 1..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 370 AA; 42107 MW; 70438C6214640D23 CRC64;
MEPHQGPASP PRDHSYTSNP QLPLAPEQLR RIEVNRMKAK SLREQHDAEA RSGALSRGSI
AAGQKRPYLA ISPSKPPSSS RDARSSKSNG RPLDEIRPAR NFAKYVEYDL SKMTDTKGGF
LTAEDDPHNK VLNSGERDEK PAHMTLKEWE RHQLLQSLRR DKAGPFEPGL SVLNTKEQKS
CRECGSIEID WKWEETLKCA VCNSCKEKFP EKYSLLTKTE AKEDYLLTDP ELKDEELLPH
LEKPNPHKAT WNNMMLYLRF QVEEYAFSPK KWGSPEALDA EFEKREATKK RQREAKFKSK
LHDLKKRTRV EAYRRSRQAA AGEGAGGHFG DDLGGGKHVH QWGRLVDNPE TGIGVKTCVD
CGMEIEELEF
//
