ID A0A0G2JA34_9EURO Unreviewed; 547 AA.
AC A0A0G2JA34;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Serine/threonine-protein kinase PRP4 {ECO:0000313|EMBL:KKZ65036.1};
GN ORFNames=EMCG_09059 {ECO:0000313|EMBL:KKZ65036.1};
OS Emmonsia crescens UAMH 3008.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emmonsia.
OX NCBI_TaxID=1247875 {ECO:0000313|EMBL:KKZ65036.1, ECO:0000313|Proteomes:UP000034164};
RN [1] {ECO:0000313|Proteomes:UP000034164}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 3008 {ECO:0000313|Proteomes:UP000034164};
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKZ65036.1}.
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DR EMBL; LCZI01000705; KKZ65036.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G2JA34; -.
DR VEuPathDB; FungiDB:EMCG_09059; -.
DR Proteomes; UP000034164; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 4.10.280.110; Pre-mRNA processing factor 4 domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR014906; PRP4-like.
DR InterPro; IPR036285; PRP4-like_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19846:SF0; SFM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR19846; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF08799; PRP4; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00500; SFM; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF158230; PRP4-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:KKZ65036.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:KKZ65036.1};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 65..118
FT /note="Pre-mRNA processing factor 4 (PRP4)-like"
FT /evidence="ECO:0000259|SMART:SM00500"
FT REPEAT 295..336
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 337..378
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 379..413
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 512..547
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 85..112
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 547 AA; 59726 MW; DDFC8C093623AA55 CRC64;
MHPARRAYVE DAPEDTEMGV DLSNIPMDRD YDMPSAAAGI PPEKASAILS QFSRRRRAAA
IAVPTEDGRV RARLRELGHP ITLFGEDATD RRDRLRELLT DLEEQKEAAG VATGEEGEDV
LMKEGEGEET EEGEGEEEFY TAGGPELLEA RKKIARYSLP RAKARVERQK EESTIPLRTH
IKHRKAIKEK LQSFDLYGSQ IAGERPVSIT RFAPNGQILA AGNWGGGIKL LNVPNLEERA
TLRGHTDRVG GISWFPGATK PESNVSESSV NLASGGGEGN VHLWSLTQDT PITTLSGHSG
RVCRVEFHPS GDYLASASYD TTWRLWDVAT STELLLQEGH SREVYSLAFN PDGSLLASGG
LDSYGRIWDL RTGRTVMILE GHIREIYGLD WGADGYRVLS GSADGWVKCW DIRQVRCTGG
VGAHRGVVSD LRWYKGTESA SSYLPSISLQ DQNDVAIDNP VTLSTPVGDQ SSSSSLSQPV
QPKKSGTFFV SSGFDKNVNV FSADDWSLVK SLSGHSGNVL SVDVSDDVKW IASCGHDRTV
KLWGIDG
//
