ID A0A0G2JEF6_MOUSE Unreviewed; 149 AA.
AC A0A0G2JEF6;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 2.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Leucine-rich repeat flightless-interacting protein 2 {ECO:0000256|ARBA:ARBA00040512};
DE Flags: Fragment;
GN Name=Lrrfip2 {ECO:0000313|Ensembl:ENSMUSP00000142753.3,
GN ECO:0000313|MGI:MGI:1918518};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000142753.3, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0007829|PubMed:17242355}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=17242355; DOI=10.1073/pnas.0609836104;
RA Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.;
RT "Large-scale phosphorylation analysis of mouse liver.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
RN [2] {ECO:0007829|PubMed:18630941}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18630941; DOI=10.1021/pr800223m;
RA Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.;
RT "Specific phosphopeptide enrichment with immobilized titanium ion affinity
RT chromatography adsorbent for phosphoproteome analysis.";
RL J. Proteome Res. 7:3957-3967(2008).
RN [3] {ECO:0007829|PubMed:19144319}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19144319; DOI=10.1016/j.immuni.2008.11.006;
RA Trost M., English L., Lemieux S., Courcelles M., Desjardins M.,
RA Thibault P.;
RT "The phagosomal proteome in interferon-gamma-activated macrophages.";
RL Immunity 30:143-154(2009).
RN [4] {ECO:0000313|Ensembl:ENSMUSP00000142753.3, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000142753.3,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [5] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [6] {ECO:0000313|Ensembl:ENSMUSP00000142753.3}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000142753.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the LRRFIP family.
CC {ECO:0000256|ARBA:ARBA00008275}.
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DR AlphaFoldDB; A0A0G2JEF6; -.
DR jPOST; A0A0G2JEF6; -.
DR ProteomicsDB; 351619; -.
DR Antibodypedia; 28249; 209 antibodies from 26 providers.
DR Ensembl; ENSMUST00000196703.6; ENSMUSP00000142753.3; ENSMUSG00000032497.20.
DR AGR; MGI:1918518; -.
DR MGI; MGI:1918518; Lrrfip2.
DR VEuPathDB; HostDB:ENSMUSG00000032497; -.
DR GeneTree; ENSGT00530000063564; -.
DR ChiTaRS; Lrrfip2; mouse.
DR Proteomes; UP000000589; Chromosome 9.
DR Bgee; ENSMUSG00000032497; Expressed in primary oocyte and 259 other cell types or tissues.
DR ExpressionAtlas; A0A0G2JEF6; baseline and differential.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR019139; LRRFIP1/2.
DR PANTHER; PTHR19212; LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN; 1.
DR PANTHER; PTHR19212:SF6; LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 2; 1.
DR Pfam; PF09738; LRRFIP; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Proteomics identification {ECO:0007829|EPD:A0A0G2JEF6,
KW ECO:0007829|MaxQB:A0A0G2JEF6};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT REGION 1..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..61
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..81
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000142753.3"
FT NON_TER 149
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000142753.3"
SQ SEQUENCE 149 AA; 16681 MW; 1DE5E551CFC2F123 CRC64;
AEARLAAKRA ARAEARDIRM RELERQQREP SEYSYYSSRA SSSRSSPVPI DDDTASIVSS
DRASRGRRES VLDEKSDKQY AENYTRPSSR NSASATTPLS GNSSRRGSGD TSSLIDPDTS
LSELRDIYDL KDQIHDVEGR YMQGLKELK
//
