ID A0A0G2JFZ0_MOUSE Unreviewed; 129 AA.
AC A0A0G2JFZ0;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 4.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Cyclin G associated kinase {ECO:0000313|Ensembl:ENSMUSP00000143359.2};
DE Flags: Fragment;
GN Name=Gak {ECO:0000313|Ensembl:ENSMUSP00000143359.2,
GN ECO:0000313|MGI:MGI:2442153};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000143359.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000143359.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000143359.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000143359.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000143359.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR ProteomicsDB; 344984; -.
DR Antibodypedia; 22165; 363 antibodies from 34 providers.
DR Ensembl; ENSMUST00000200204.2; ENSMUSP00000143359.2; ENSMUSG00000062234.15.
DR AGR; MGI:2442153; -.
DR MGI; MGI:2442153; Gak.
DR VEuPathDB; HostDB:ENSMUSG00000062234; -.
DR GeneTree; ENSGT00940000159527; -.
DR ChiTaRS; Gak; mouse.
DR Proteomes; UP000000589; Chromosome 5.
DR Bgee; ENSMUSG00000062234; Expressed in embryonic post-anal tail and 249 other cell types or tissues.
DR ExpressionAtlas; A0A0G2JFZ0; baseline and differential.
DR Gene3D; 2.60.40.1110; -; 1.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR014020; Tensin_C2-dom.
DR PANTHER; PTHR23172; AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED; 1.
DR PANTHER; PTHR23172:SF34; CYCLIN-G-ASSOCIATED KINASE; 1.
DR Pfam; PF10409; PTEN_C2; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR PROSITE; PS51182; C2_TENSIN; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:A0A0G2JFZ0,
KW ECO:0007829|MaxQB:A0A0G2JFZ0};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 1..72
FT /note="C2 tensin-type"
FT /evidence="ECO:0000259|PROSITE:PS51182"
FT REGION 73..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..121
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000143359.2"
FT NON_TER 129
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000143359.2"
SQ SEQUENCE 129 AA; 14880 MW; EFE5582DAF7A865D CRC64;
XVLIIIYHAR ATLGGRLQAK MASMKMFQIQ FHTGFVPRNA TTVKFAKYDL DACDIQEKYP
DLFQVNLEVE VEPRDRPSRE APPWENTSLR GLNPKILFSN REEQQDILSK FEEKEPETGL
DNTSPKESQ
//
