ID A0A0G2JGK0_MOUSE Unreviewed; 110 AA.
AC A0A0G2JGK0;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Elongator complex protein 6 {ECO:0000256|ARBA:ARBA00020263};
GN Name=Elp6 {ECO:0000313|Ensembl:ENSMUSP00000143595.2,
GN ECO:0000313|MGI:MGI:1919349};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000143595.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000143595.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000143595.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000143595.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000143595.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA
CC biosynthesis. {ECO:0000256|ARBA:ARBA00005043}.
CC -!- SIMILARITY: Belongs to the ELP6 family.
CC {ECO:0000256|ARBA:ARBA00008837}.
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DR AlphaFoldDB; A0A0G2JGK0; -.
DR SMR; A0A0G2JGK0; -.
DR ProteomicsDB; 320064; -.
DR Antibodypedia; 48948; 110 antibodies from 14 providers.
DR Ensembl; ENSMUST00000198247.5; ENSMUSP00000143595.2; ENSMUSG00000054836.13.
DR AGR; MGI:1919349; -.
DR MGI; MGI:1919349; Elp6.
DR VEuPathDB; HostDB:ENSMUSG00000054836; -.
DR GeneTree; ENSGT00390000011734; -.
DR UniPathway; UPA00988; -.
DR Proteomes; UP000000589; Chromosome 9.
DR Bgee; ENSMUSG00000054836; Expressed in dentate gyrus of hippocampal formation granule cell and 224 other cell types or tissues.
DR ExpressionAtlas; A0A0G2JGK0; baseline and differential.
DR GO; GO:0033588; C:elongator holoenzyme complex; IEA:InterPro.
DR GO; GO:0002098; P:tRNA wobble uridine modification; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR018627; ELP6.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR16184; ELONGATOR COMPLEX PROTEIN 6; 1.
DR PANTHER; PTHR16184:SF6; ELONGATOR COMPLEX PROTEIN 6; 1.
DR Pfam; PF09807; ELP6; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:A0A0G2JGK0,
KW ECO:0007829|MaxQB:A0A0G2JGK0};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
SQ SEQUENCE 110 AA; 12297 MW; 01672B706EBE14B5 CRC64;
MFPELNNLLS TTPDKTEQGT LTLLCDAKTD GSFLVHHFLS FYLKANCKVC FVALVQSFSH
YNIVGQKLGV SLTAARDRGQ LVFLEGLKSS VEVLFHSQDE PHPLQFLRTP
//
