ID A0A0G2JM79_HUMAN Unreviewed; 392 AA.
AC A0A0G2JM79;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Nostrin {ECO:0000313|Ensembl:ENSP00000478690.1};
DE Flags: Fragment;
GN Name=NOSTRIN {ECO:0000313|Ensembl:ENSP00000478690.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000478690.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000478690.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT 4.";
RL Nature 434:724-731(2005).
RN [2] {ECO:0007829|PubMed:23186163}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=23186163;
RA Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA Mohammed S.;
RT "Toward a comprehensive characterization of a human cancer cell
RT phosphoproteome.";
RL J. Proteome Res. 12:260-271(2013).
RN [3] {ECO:0000313|Ensembl:ENSP00000478690.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2022) to UniProtKB.
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DR EMBL; AC069137; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC208170; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0G2JM79; -.
DR SMR; A0A0G2JM79; -.
DR MassIVE; A0A0G2JM79; -.
DR Ensembl; ENST00000610378.4; ENSP00000478690.1; ENSG00000275326.4.
DR Ensembl; ENST00000611498.4; ENSP00000484358.1; ENSG00000275326.4.
DR Ensembl; ENST00000614842.4; ENSP00000483177.1; ENSG00000275326.4.
DR Ensembl; ENST00000618893.1; ENSP00000480854.1; ENSG00000275326.4.
DR Ensembl; ENST00000620516.4; ENSP00000481062.1; ENSG00000275326.4.
DR HGNC; HGNC:20203; NOSTRIN.
DR ChiTaRS; NOSTRIN; human.
DR Proteomes; UP000005640; Unplaced.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd11823; SH3_Nostrin; 1.
DR Gene3D; 6.10.140.470; -; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR035656; Nostrin_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14167:SF31; NOSTRIN; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF46585; HR1 repeat; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS51860; REM_1; 1.
DR PROSITE; PS50002; SH3; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Proteomics identification {ECO:0007829|MaxQB:A0A0G2JM79,
KW ECO:0007829|PeptideAtlas:A0A0G2JM79};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..146
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 178..258
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 324..383
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT COILED 192..262
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000478690.1"
SQ SEQUENCE 392 AA; 44841 MW; FBB25D055912819B CRC64;
LDNEVEKTAN LVISNWNQQI KAKKKLMVST KKHEALFQLV ESSKQSMTEK EKRKLLNKLT
KSTEKLEKED ENYYQKNMAG YSTRLKWENT LENCYQSILE LEKERIQLLC NNLNQYSQHI
SLFGQTLTTC HTQIHCAISK IDIEKDIQAV MEETAILSTE NKSEFLLTDY FEEDPNSAMD
KERRKSLLKP KLLRLQRDIE KASKDKEGLE RMLKTYSSTS SFSDAKSQKD TAALMDENNL
KLDLLEANSY KLSSMLAELE QRPQPSHPCS NSIFRWREKE HTHSYVKISR PFLMKRLENI
VSKASSGGQS NPGSSTPAPG AAQLSSRLCK ALYSFQARQD DELNLEKGDI VIIHEKKEEG
WWFGSLNGKK GHFPAAYVEE LPSNAGNTAT KA
//
