ID A0A0G2JP96_HUMAN Unreviewed; 506 AA.
AC A0A0G2JP96;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Leukocyte immunoglobulin-like receptor subfamily A member 1 {ECO:0000313|Ensembl:ENSP00000483224.1};
GN Name=LILRA1 {ECO:0000313|Ensembl:ENSP00000483224.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000483224.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000483224.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000483224.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2022) to UniProtKB.
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DR EMBL; CU024913; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CU234142; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0G2JP96; -.
DR SMR; A0A0G2JP96; -.
DR MassIVE; A0A0G2JP96; -.
DR Ensembl; ENST00000613536.4; ENSP00000480299.1; ENSG00000274935.5.
DR Ensembl; ENST00000616368.4; ENSP00000483224.1; ENSG00000277398.5.
DR HGNC; HGNC:6602; LILRA1.
DR ChiTaRS; LILRA1; human.
DR Proteomes; UP000005640; Unplaced.
DR CDD; cd05751; IgC2_D1_LILR_KIR_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR016332; A1B_glyco/leuk_Ig-like_rcpt.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11738:SF165; LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 1-RELATED; 1.
DR PANTHER; PTHR11738; MHC CLASS I NK CELL RECEPTOR; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR PIRSF; PIRSF001979; Alpha_1B_glycoprot_prd; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR001979-1};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A0G2JP96};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 44..115
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 442..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 66..115
FT /evidence="ECO:0000256|PIRSR:PIRSR001979-1"
FT DISULFID 162..214
FT /evidence="ECO:0000256|PIRSR:PIRSR001979-1"
SQ SEQUENCE 506 AA; 55059 MW; 0E7794B2DCAA1527 CRC64;
MHRGLIHPQS RAVGGDAMTP IVTVLICLRL SLGPRTHVQA GTLPKPTLWA EPGSVITQGS
PVTLWCQGIL ETQEYRLYRE KKTAPWITRI PQEIVKKGQF PIPSITWEHT GRYRCFYGSH
TAGWSEPSDP LELVVTGAYI KPTLSALPSP VVTSGGNVTL HCVSQVAFGS FILCKEGEDE
HPQCLNSQPR THGWSRAIFS VGPVSPSRRW SYRCYAYDSN SPHVWSLPSD LLELLVLGVS
KKPSLSVQPG PIVAPGESLT LQCVSDVSYD RFVLYKEGER DFLQLPGPQP QAGLSQANFT
LGPVSRSYGG QYRCSGAYNL SSEWSAPSDP LDILIAGQFR GRPFISVHPG PTVASGENVT
LLCQSWGPFH TFLLTKAGAA DAPLRLRSIH EYPKYQAEFP MSPVTSAHSG TYRCYGSLSS
NPYLLSHPSD SLELMVSGAA ETLSPPQNKS DSKAGAANTL SPSQNKTASH PQDYTVENLI
RMGIAGLVLV VLGILLFEAQ HSQRSL
//
