ID A0A0G2K9L9_RAT Unreviewed; 5589 AA.
AC A0A0G2K9L9;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Midasin {ECO:0000256|ARBA:ARBA00017143, ECO:0000256|PIRNR:PIRNR010340};
GN Name=Mdn1 {ECO:0000313|Ensembl:ENSRNOP00000075047.2,
GN ECO:0000313|RGD:1306394};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000075047.2, ECO:0000313|Proteomes:UP000002494};
RN [1] {ECO:0000313|Ensembl:ENSRNOP00000075047.2, ECO:0000313|Proteomes:UP000002494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000075047.2,
RC ECO:0000313|Proteomes:UP000002494};
RX PubMed=15057822; DOI=10.1038/nature02426;
RG Rat Genome Sequencing Project Consortium;
RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D.,
RA Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L.,
RA Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D.,
RA Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M.,
RA Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C.,
RA Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J.,
RA Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H.,
RA Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X.,
RA Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q.,
RA Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P.,
RA Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A.,
RA Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C.,
RA Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J.,
RA Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F.,
RA Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A.,
RA Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A.,
RA Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J.,
RA Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E.,
RA Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C.,
RA Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L.,
RA Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W.,
RA Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y.,
RA Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V.,
RA Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M.,
RA Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S.,
RA Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B.,
RA Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R.,
RA Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J.,
RA Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D.,
RA Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S.,
RA Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S.,
RA Mockrin S., Collins F.S.;
RT "Genome sequence of the Brown Norway rat yields insights into mammalian
RT evolution.";
RL Nature 428:493-521(2004).
RN [2] {ECO:0000313|Ensembl:ENSRNOP00000075047.2}
RP IDENTIFICATION.
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000075047.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Nuclear chaperone required for maturation and nuclear export
CC of pre-60S ribosome subunits. {ECO:0000256|PIRNR:PIRNR010340}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}. Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the midasin family.
CC {ECO:0000256|ARBA:ARBA00007188, ECO:0000256|PIRNR:PIRNR010340}.
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DR STRING; 10116.ENSRNOP00000075047; -.
DR PhosphoSitePlus; A0A0G2K9L9; -.
DR Ensembl; ENSRNOT00000090799.2; ENSRNOP00000075047.2; ENSRNOG00000047513.4.
DR AGR; RGD:1306394; -.
DR RGD; 1306394; Mdn1.
DR VEuPathDB; HostDB:ENSRNOG00000047513; -.
DR eggNOG; KOG1808; Eukaryota.
DR GeneTree; ENSGT00550000074802; -.
DR InParanoid; A0A0G2K9L9; -.
DR OMA; ILEQWHR; -.
DR Proteomes; UP000002494; Chromosome 5.
DR Bgee; ENSRNOG00000047513; Expressed in spleen and 19 other cell types or tissues.
DR ExpressionAtlas; A0A0G2K9L9; baseline and differential.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0045111; C:intermediate filament cytoskeleton; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; ISO:RGD.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IBA:GO_Central.
DR CDD; cd00009; AAA; 2.
DR CDD; cd01460; vWA_midasin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 6.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR040848; AAA_lid_7.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR029317; KRBA1_rpt.
DR InterPro; IPR048617; MDN1_AAA_lid_4.
DR InterPro; IPR012099; Midasin.
DR InterPro; IPR041190; Midasin_AAA_lid_5.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR48103:SF2; MIDASIN; 1.
DR PANTHER; PTHR48103; MIDASIN-RELATED; 1.
DR Pfam; PF07728; AAA_5; 8.
DR Pfam; PF17865; AAA_lid_5; 1.
DR Pfam; PF17867; AAA_lid_7; 3.
DR Pfam; PF21108; MDN1_4th; 1.
DR PIRSF; PIRSF010340; Midasin; 2.
DR SMART; SM00382; AAA; 6.
DR SMART; SM01258; KRBA1; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 6.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 1: Evidence at protein level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR010340};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|PIRNR:PIRNR010340};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR010340};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR010340};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A0G2K9L9};
KW Reference proteome {ECO:0000313|Proteomes:UP000002494}.
FT DOMAIN 5377..5576
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 4522..4545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4696..5182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5201..5253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4696..4738
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4753..4772
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4773..4806
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4813..4827
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4835..4858
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4871..4885
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4899..4913
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4959..4982
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5013..5029
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5073..5095
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5096..5127
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5148..5169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5204..5221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5222..5253
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5589 AA; 630061 MW; F332AC54E65BD276 CRC64;
MEHLSVDLVA GPLRLIATKN EKSSGELNRF LAKSVWTPQD RQCILNSLAQ LLLDKDYTLL
LGRQLRPILL DLLERNAKAI KTGGQVNHDL HERLSVSMSK LIGSHPDVLP FALRYFKDTY
PVFQRLFLES SDANPVRYGR RRMKLRDLME AAHIFLQHKQ PVFRELWDWS VCVPLLRSHD
ALVRWHTANC LALVTCMNEE HKLSFLRKIF SSEELVHFRL RLLEEAQLQD LEKALVLANP
EASLWHKGEE PQYIQGHLVS ADLSSSVAAV CGVVLPKQSS SPAEQQTSDR SSSRDQELAL
TSFVLVESVC KNLQMLAVAV ASQNAVLLEG PIGSGKTSLV EHLAAVTGRT KPPQLLKVQL
GDQTDSKMLL GMYRCTDVPG EFVWQPGTLT QAATKGHWIL LEDIDYAPLD VVSVLIPLLE
NGELLIPGQG DCLKVAPTFQ LFATRRLLSC GGSWYRPLNS HAAMLDKYWT KIHLHNLDKK
DLREVLQNRY PSLLTATDHL LDIYIELTGE KHCCPSIGCD EAPQEVSEAE GENRRVALEG
RELSLRDLLN WCNRVAHGFD STSSTALLNV FQEALDCFTA MLSEQTKKLK MAEIIGSKLN
ISKKKAEFFC KLYKPEIVIN ELDVQVGRVR LLRKQSEVVR IQKEKCSFAA TRPSSVLLEQ
LAVCVSQGEP VLLVGETGTG KTSAVQHLAH ATGQHLRVVN MNQQSDTADL LGGFKPVDHK
LIWLPLRETF EELFVQTFSK KQNFTFLGHI QTCYRQKRWH DLLKLMQHVQ KSAITKEGKE
SQPGLLLKEK WEAFGLRLNH AQQQMKMTEN ALLFAFVEGT LAQAIKKGEW ILLDEINLAA
PETLECLSGL LEGSSGSLVL LDRGDTEPLV RHPDFRLFAC MNPATDVGKR NLPPGIRNRF
TELYVEELES KEDLHILIVD YLKGLSVSRS AVQGIVNFYT ALRKESKTKL VDGTGHRPHY
SLRTLCRALR FAASNPCGNI QRSLYEGFCL GFLTQLDRAS HPVVQKLICQ HIISGNVKSL
LKQPIPEPKG GRLIQVEGYW ISVGDKEPKI DETYVLTPSV KLNLRDIARV VSAGTYPVLI
QGETSVGKTS LIRWLAAATG NHCVRINNHE HTDIQEYIGC YTSDTSGKLV FNEGVLIDAM
RKGYWIVLDE LNLAPTDVLE ALNRLLDDNR ELLITETQEV VRAHPRFMLF ATQNPPGLYG
GRKVLSRAFR NRFVELHFDE LPSSELETIL HKRCSLPPSY CSKLVKVMLE LQSYRRRSSV
FAGKQGFIAL RDLFRWAERY RLAEQTEKDY DWLQHLANDG FMLLAGRVRK QEEADVIQEV
LEKHFKKKLC PQSLFSKENV LKLLSKSSTQ TSVLESKFSH VVWTEGMRRL AVLVGRALEF
GEPVLLVGDT GCGKTTVCQL FSALSNQKLY SVNCHLNMET SDFLGGLRPV RQKPNDKEEP
DTRLFEWHDG PLVLAMKEDS FFLLDEISLA DDSVLERLNS VLEVEKCLVL AEKGSPESKD
TEVELLTAGK HFRILATMNP GGDFGKKELS PALRNRFTEI WCPQSTKRED LVQIINHNLR
PGLSLARAGH KGADIAEVML DFITWLTHQE FGRKCVVSIR DILSWVNFMN TMAEEAAVKR
LETISTVTSF VHAACLVYID GIGSGVTSSG FGTALLAREE CLKFLIKKLS KVVRLTERQK
DELKIYDRLK HKEFTSVDDL WGVHPFFIPR GPVLNGHTIA DYALSAGTTA MNAQRLLRAA
KLNKPILLEG SPGVGKTSLV AALAKASGNT LVRINLSEQT DITDLFGADL PVEGGKGGEF
AWCDGPLLAA LKAGHWVVLD ELNLASQSIL EGLNACFDHR GEIYVPELGM SFQVQHEKTR
IFGCQNPFRQ GGGRKGLPKS FLNRFTQVFV DPLTVVDMEF IASTLFPAID RNIVKKMVAF
NNHIDHEVTV EKKWGQKGGP WEFNLRDLFR WCQLMLVDQS PGCYDPGQHV FLIYGERMRT
REDKEKVITV FKDVFASNSM PYIGTRLFHI TPYDVQIGYS VLSRSSYVPH PSRRPLSLLH
QSLQSLEPIM KCVQMSWMVI LVGPASVGKT SLVQLLAHLT GHTLKIMAMN SAMDTTELLG
GFEQVDIIRP WRLLLEKVER AVRVLLRDSL LINADDTEVV LRAWSHFLLT YRPKCLGEDG
KGVTIEIVNK LEAVLLLLQR LNNKINSYSK ADFAKLVEDF RTFGVKLLQS TSGRSHGSFE
WVDSMLVQAL KSGDWLLMDN VNFCNPSVLD RLNALLEPGG VLTINERGMV DGSTCTVTPN
PNFRLFLSMD PVHGEISRAM RNRGLEIYIS EEKEGSILEN LDLKVLLHSL GLVGDSLCNV
LLALHTGVQS LVKGSPTSSV STLSHTAILI VQYLQRGLSL DKAFFEACWE VYVCSQHSAA
NQKLVQALLE SHTASLRAKE TWGHSILATG LWPDSVPSAL FATEDSRLAV VRSDGQILAY
CLNRLSLRTI SWTRSQPLTL QDLEHIMQTS NPENLTFNAV EVDTCWVDEP EVLAMAVKLL
IERATNQDWM LRVKWLSHLA KNIPQGLEAV RSHVEASATA LRKFYAASLS AGVSNVLKIL
QTNITDDFVI PWDPRWNMQA LDIIRNSLDF DPQSDQAEQL FELLESVANK TIIYLDREKR
IFTEANLLSV GSKKLRSNAL RMSFEFHKDP ETYHSPPHEI VANLAAFFEL IDGLILLWVQ
SPQGMVPDAH VNKILGSMQW RDRFWAVADA VTVDASGLAL LALHWHWVSK HLIRQIPQLL
VNHEDKYYKE VQMVSEQIHS CLGSPAGSFP GVKKLQAFLG RPFPFKDKLV VDCFSQLQAL
NRALSIGERL PVFGECGWQE DINRLQVVAS EWNLKKSLLQ TWGLILRANI LEDVNLDELK
NLVNTQCSEL KTRGLSHGFL EKAHEASSPS QPDLSSLAHL TRRVQLWPVT EYLAVLWQYR
VTAGFVTQAC LRRSSTHQQM DEEISHCITF CLKHTPIAPQ KLWNLWSLLH IQKLSAQEVS
CLWSELFTST FGSSWSSPVT TNPEYWLTWS PLPNAQPQEM PRSRWDSTLK GPGSLCRAVF
SKCCFGVLTN SSSGSSWDVS GLPLLSSSHV TLGEWVERAQ QLQDIRSLLW TNMTVPSVAE
FRRTDSRLQG LVLCRYLLGL TELLPAPQRQ EYMQNCEHLL LGNTQAFHHV DQTLANIGGQ
EVLPKELFCL LLTSLHYFIG EGESKQNLRE AARRGRLWVS LGLLQIQTWV PQTRFDPAVK
KAYKLKYAQE ELCQLQCELK TRNLLSHLQT GRDLEDDIIA SHSHPHIRLL PQRISHLENL
VHSLSKKQAF RPHLPSYETL VQEIHHYVTS IAKVTAVQDL LMRLLQALHT DGPKSAQVLQ
NLLKEEASWQ QSHQQFRKRL VEEYALYPDT VTPLQASILQ LQHGMRLVAS EVHASLHSSV
ICTEHVEALA MAVLAFPSVG PSFPTYHAHA DALCSVNSAE ALRGLGKLMV KRAARKEEGK
NQQPYPTREQ LLMNALLYLR SHVLCKGELD QRALLLFRHL CQEIINEWDE QERIAQEKAE
QESSLYRCRS RSCRTALSEE EEDELELRKL FPLHEKDFAD ILMEPTLEEK RRASDGREEA
ATDPALLSQS SMQAVMLIHQ QLCLSFARSL WYQQSVPAHE AEHYLSLFFS CYQTGASLLT
HFYHLMGVEM NDQLLGSQLL ACTLSSNTLC GEATSDLMMK PDGPYDFYQH PNVAEARQCQ
PVLQGLSEAV SQLLQDWPEH PVLEQLLVVM DRIRGFPLSS PISKLLNGLE ILLAKAQDWE
ENASRELSLR KHLDLVSQMI IRWRKLELNC WSMSLDNTMR RHTEKSTKHW FSIYQMLEKH
MQERTEEQED DKPMTLMLLV STLQAFIEGS SLGEFHVRLQ MLLVFHCHVL LMPQVEGKDS
LCSVLWNLYH FYKQFLDPVQ AKIVELRSPI EKELKEFVKI SKWNDVSFWS IKQSVEKTHR
TLFKFMKKFE AVLNEPCQSC LVESNKEEQP DCLPKPTEEA TMETSPIQAL NSALRETLLA
QPIAWQPSGT EQCQDAVGPL SMEGELLRRL PRLSKRMRKV CLIFMKESPL PHLVESLDQF
TGGVISSVSE LQSLTVDPSA EKEKQHSEAK HILMQKHRAL SDLFKHLAKI GLSYRKGLAW
ARSKSPQELL HLHPLDLQSA LSIVSSTREA DSRLLTEISS LWDGCQKYFY RSLARLTRLT
AALATPAKEI SMGNVDRCKG FSAHLMKLLI RQRHSLTTLT EQWIILRNLL SCVQEIHSRL
IGPPVYPVAF PPQDSVQQWT ERLQHLAMQS QILLEQFSWL LQCCPSVGPT EGHSDAPFQE
HPSASHLEKV DTKGPIAGAM PDLLPSALSY PSPVPRSQLP SGCRMRRQDQ LWQQSTAGLT
EMLKTIKTMK AGVDKIRQQS CETLFHTWED FEVCSSGLNC LSQVSAHLQG LASLFILPGI
EVEKTDSQMA LVESLDYLRG EISKAVDDFT AWKARLFIAH KQGGNQMLEE SFVEDFSEQV
ESAIRAILCT IQNLAERNSK KAEDSAADKR LQEEDGGKEE EASFKSLQPG HLTKLLEDDF
WASVSTLHVQ KIISSVSELL ERLKSCSEDG NTTKHKVFSQ SCGLLVRLIP MLCGFSDLIL
FFLTISLATH RSTAKLLSVL TQTFTELALK GFCLPKELIE DSAGEGAMQF HDYEGGGIGD
GEGVKDVSDR IENEEQVEDT FQKGQEKDKE DLDSKPDTKG EDSAVEMSED FDGKMHDGEL
EQEEDDEKSD SEDGDLDKQM GNLNGEEADK LDERLWGDDE EEDEDDDGKG EEAGPGMDEE
DSELVAKDDN LDAGNLNKNK KHQGEEEDSE PEDVEQGQEK INEQMDEREY DESEVDPYHG
SQEQLPEPEA LDLPDDLKLD SEDRSAGEDT DNEEAEEENP LEIKEKTVDM EEIDREVEEP
DAAQSEGERP PAPDEGPGEG EESMDTGADD QDKDTASHAE EQEEEEEGEE GEEEEEEEDR
AATDGSGESG VSPVDKDLQP QKEEEEGEKS DAEEQVPEAT ERKEHDSCGQ TGVDNVQSAQ
AVELAGAAPE KEQGKEEHGS GAADANQAEG HESNFIARLS SQQHTNKNTQ SFKRRPGQAD
NERSIGDPNE HVRKRLRTVD TDRKTEQEPA QPQAQVEDAD TFEHIQQGSD AYDAQTYDVA
SSEQQQTTKA SGEDQEEEEK EDILMDTEEE LIRAEDTEQL KPEAVRSETA TASGSSEMEV
DMQTLKTKED EDPRTTTSHQ EIESERPERS RESTIHTLHQ LLVDTVFQPF LKDISELRQE
MERQLETWQT HNYGNAEEEK AAAEMWQNYL VLTAALSQQL CEQLRLLLEP TQAAKLRGDY
RTGKRLNMRK IIPYIASQFR KDRIWLRRTK PSKRQYQICL AIDDSSSMVD NHTKQLAFES
LAVIGNALTL LEVGQIAVCS FGESVKLLHP FHEQFNDSSG SQILRLCKFQ QRKTKIAQFL
ESVAIMFAAA QKLSQNTSPE TAQLLLIVSD GRGLFLEGKD RVLAAVQAAQ NANIFVIFVV
LDNPNSRDSI LDIKVPIFKG PGEMPEIRSY MEEFPFPFYI ILRDVNALPE TLSDALRQWF
ELVTASDHS
//
