ID   A0A0G2LB90_MOUSE        Unreviewed;       912 AA.
AC   A0A0G2LB90;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Tubulin tyrosine ligase-like family, member 7 {ECO:0000313|Ensembl:ENSMUSP00000043753.8};
GN   Name=Ttll7 {ECO:0000313|Ensembl:ENSMUSP00000043753.8,
GN   ECO:0000313|MGI:MGI:1918142};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000043753.8, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000043753.8, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000043753.8,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000043753.8}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000043753.8};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; NP_001289886.1; NM_001302957.1.
DR   AlphaFoldDB; A0A0G2LB90; -.
DR   SMR; A0A0G2LB90; -.
DR   ProteomicsDB; 358968; -.
DR   Antibodypedia; 53234; 37 antibodies from 12 providers.
DR   Ensembl; ENSMUST00000037942.11; ENSMUSP00000043753.8; ENSMUSG00000036745.16.
DR   GeneID; 70892; -.
DR   AGR; MGI:1918142; -.
DR   CTD; 79739; -.
DR   MGI; MGI:1918142; Ttll7.
DR   VEuPathDB; HostDB:ENSMUSG00000036745; -.
DR   GeneTree; ENSGT00940000159078; -.
DR   OMA; MKIKFPG; -.
DR   OrthoDB; 7265at2759; -.
DR   BioGRID-ORCS; 70892; 1 hit in 45 CRISPR screens.
DR   Proteomes; UP000000589; Chromosome 3.
DR   Bgee; ENSMUSG00000036745; Expressed in facial nucleus and 176 other cell types or tissues.
DR   ExpressionAtlas; A0A0G2LB90; baseline and differential.
DR   GO; GO:0043014; F:alpha-tubulin binding; IEA:Ensembl.
DR   GO; GO:0048487; F:beta-tubulin binding; IEA:Ensembl.
DR   GO; GO:0070740; F:tubulin-glutamic acid ligase activity; IEA:Ensembl.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   InterPro; IPR004344; TTL/TTLL_fam.
DR   PANTHER; PTHR12241; TUBULIN POLYGLUTAMYLASE; 1.
DR   PANTHER; PTHR12241:SF147; TUBULIN POLYGLUTAMYLASE TTLL7; 1.
DR   Pfam; PF03133; TTL; 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   PROSITE; PS51221; TTL; 1.
PE   1: Evidence at protein level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Proteomics identification {ECO:0007829|MaxQB:A0A0G2LB90,
KW   ECO:0007829|ProteomicsDB:A0A0G2LB90};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   REGION          547..570
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          658..688
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          379..447
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        547..563
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   912 AA;  105491 MW;  17FE5E18A1225C36 CRC64;
     MPSLPQDGVI QGSSPVDLGT ELPYQCTMKR KVRKKKKKGI ITANVAGTKF EIVRLVIDEM
     GFMKTPDEDE TSNLIWCDAA VQQEKITDLQ NYQRINHFPG MGEICRKDFL ARNMTKMIKS
     RPMDYTFVPR TWIFPSEYTQ FQNYVKELKK KRKQKTFIVK PANGAMGHGI SLIRNGDKVP
     SQDHLIVQEY IEKPFLMEGY KFDLRIYILV TSCDPLKIFL YHDGLVRMGT EKYIPPNESN
     LTQLYMHLTN YSVNKHNERF ERNETEDKGS KRSIKWFTEF LQANQHDVTK FWSDISELVV
     KTLIVAEPHV LHAYRMCRPG QPPGSESVCF EVLGFDILLD RKLKPWLLEI NRAPSFGTDQ
     KIDYDVKRGV LLNALKLLNI RTSDKRKNLA KQKAEAQRRL YGQNPVRRLS PGSSDWEQQR
     HQLERRKEEL KERLLQVRKQ VSQEEHENRH MGNYRRIYPP EDKALLEKYE GLLAVAFQTF
     LSGRAASFQR EMNNPLKKMR EEDLLDLLEQ CEIDDEKLMG KTGRVRGPKP LCCMPECAEV
     TKKQKYYGSS DSSYDSSSSS SNSELDENEK ELCQKRLDQV PYSLKHTSHC KIIQQSSGSH
     NLIYSESPVY LTTLVFLSEF PDSMRRSVSC PRSISAHLPS RGDVRPFSSQ QVIPLARPTS
     ASRSHSLNRA SSYARHLPHG SDTGSTNTLN ESLRQLKTKE QEDDLTSQTL FVLKDMRIRF
     PGKSDAESEL LIEDIMDNWK HYKTKVASYW LIKLDSVKQR KVLDIVKSSI RTVLPRIWRV
     PDAEELSLYR IFNRVFNRLL WSHGQGLWSC FCDSGSSWES IFSKSPEVVT PLQLQCCQRL
     VELCKQCLLV VYKYTTETRG PISGIGPDWG NSRYLLPGST QFLMRSPLYN MKYNSPGMTR
     SNVLFTSRYG RL
//