ID A0A0G3ACD4_9ACTN Unreviewed; 381 AA.
AC A0A0G3ACD4;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:AKJ09430.1};
GN ORFNames=ABB07_05165 {ECO:0000313|EMBL:AKJ09430.1};
OS Streptomyces incarnatus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=665007 {ECO:0000313|EMBL:AKJ09430.1, ECO:0000313|Proteomes:UP000035366};
RN [1] {ECO:0000313|EMBL:AKJ09430.1, ECO:0000313|Proteomes:UP000035366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL8089 {ECO:0000313|Proteomes:UP000035366};
RX PubMed=26159526;
RA Oshima K., Hattori M., Shimizu H., Fukuda K., Nemoto M., Inagaki K.,
RA Tamura T.;
RT "Draft Genome Sequence of Streptomyces incarnatus NRRL8089, which Produces
RT the Nucleoside Antibiotic Sinefungin.";
RL Genome Announc. 3:e00715-e00715(2015).
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DR EMBL; CP011497; AKJ09430.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G3ACD4; -.
DR STRING; 665007.ABB07_05165; -.
DR PATRIC; fig|665007.5.peg.1121; -.
DR Proteomes; UP000035366; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 8..62
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 332..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..355
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 381 AA; 40536 MW; 48390288D7669E2B CRC64;
MTEAVSRPTL EAVAARAGVS RATVSRVVNG GDGVREPLAR RVRQAVAELG YVPNQAARSL
VTKRHDAVAV VIAEPEARVF ADPFFALQLR GISKELTAHD NQLVLLLIEG RDDHARVARY
LSGGHVDGAL VFSLHLDDPL PGLIQDAGVP TVFGGRPGWG DDGRAAKDPG VVYVDCDNRG
GARAAVRHLV GLGRRRIAHL TGALDQTSAV DRLDGYRDVM AEVPGGNDPR LVVESDFTPA
GGERAMRELL DRCPDVDAVF AANDLTALGA LRVLRASGRR VPEDVAVIGF DDMLPVTEEA
DPPLTTVRQD IEQMGRLMAR LLLRGLSHGR DRMDGRVRAD GRDGTDVRDR PDGPGRSGTA
VDGPGAGGVV LPTTLIRRAS A
//
