ID A0A0G3AF06_9ACTN Unreviewed; 302 AA.
AC A0A0G3AF06;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=HTH tetR-type domain-containing protein {ECO:0000259|PROSITE:PS50977};
GN ORFNames=ABB07_21840 {ECO:0000313|EMBL:AKJ12571.1};
OS Streptomyces incarnatus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=665007 {ECO:0000313|EMBL:AKJ12571.1, ECO:0000313|Proteomes:UP000035366};
RN [1] {ECO:0000313|EMBL:AKJ12571.1, ECO:0000313|Proteomes:UP000035366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL8089 {ECO:0000313|Proteomes:UP000035366};
RX PubMed=26159526;
RA Oshima K., Hattori M., Shimizu H., Fukuda K., Nemoto M., Inagaki K.,
RA Tamura T.;
RT "Draft Genome Sequence of Streptomyces incarnatus NRRL8089, which Produces
RT the Nucleoside Antibiotic Sinefungin.";
RL Genome Announc. 3:e00715-e00715(2015).
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DR EMBL; CP011497; AKJ12571.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G3AF06; -.
DR STRING; 665007.ABB07_21840; -.
DR PATRIC; fig|665007.5.peg.4657; -.
DR Proteomes; UP000035366; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF226; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RV1474C; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 34..94
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 57..76
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 302 AA; 30825 MW; 32C013C35C782633 CRC64;
MSTTPSATRG TFPSTGRRPP SVSAPVSLTE RRKAETRMEI ARAAAALFVR QGLRATRAED
IAHAAGIAPR TFYRYFATKE EAVAPLYAAG AQRWAEAVRS APARLSVPEA LEHAVRHTFT
PGAGVSVASW EWVRTLIRLA DASPALRKVW AEVCQASEHT LAEILAHRIA STGSRNAGVG
SAGSGEAEAG PGDDAGCGEA EAGPGDDAGC GGAEAGPGDD AGSGQAGGVE ARRDNDAPGL
TAPAPVTPGL RFAAAVAGTA VRVAVESWAT SSSPPSGPEG PAALALRNLR SLRDFQWGDG
EG
//
