ID   A0A0G3AMA3_9ACTN        Unreviewed;      1045 AA.
AC   A0A0G3AMA3;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Helicase {ECO:0000313|EMBL:AKJ12915.1};
GN   ORFNames=ABB07_23630 {ECO:0000313|EMBL:AKJ12915.1};
OS   Streptomyces incarnatus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=665007 {ECO:0000313|EMBL:AKJ12915.1, ECO:0000313|Proteomes:UP000035366};
RN   [1] {ECO:0000313|EMBL:AKJ12915.1, ECO:0000313|Proteomes:UP000035366}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL8089 {ECO:0000313|Proteomes:UP000035366};
RX   PubMed=26159526;
RA   Oshima K., Hattori M., Shimizu H., Fukuda K., Nemoto M., Inagaki K.,
RA   Tamura T.;
RT   "Draft Genome Sequence of Streptomyces incarnatus NRRL8089, which Produces
RT   the Nucleoside Antibiotic Sinefungin.";
RL   Genome Announc. 3:e00715-e00715(2015).
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DR   EMBL; CP011497; AKJ12915.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G3AMA3; -.
DR   STRING; 665007.ABB07_23630; -.
DR   REBASE; 113721; Sin8089ORF23630P.
DR   PATRIC; fig|665007.5.peg.5032; -.
DR   Proteomes; UP000035366; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR   CDD; cd09203; PLDc_N_DEXD_b1; 1.
DR   CDD; cd18799; SF2_C_EcoAI-like; 1.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR021835; DUF3427.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR025202; PLD-like_dom.
DR   PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR   PANTHER; PTHR47962:SF7; MITOCHONDRIAL ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR   Pfam; PF11907; DUF3427; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF13091; PLDc_2; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:AKJ12915.1};
KW   Helicase {ECO:0000313|EMBL:AKJ12915.1};
KW   Hydrolase {ECO:0000313|EMBL:AKJ12915.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:AKJ12915.1}.
FT   DOMAIN          334..490
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          547..703
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1045 AA;  117807 MW;  08050A620618CF47 CRC64;
     MSRLEPIAGV YEKLITDDVR DELERFEAAG WKAIDAEVSS ESAPHVLARY IGEAVGQRLA
     QVPAEDRVKV ANRILEALTA TNTPKSSDAD SVSSIIEGPR QLLTLARQEA PGVYALRPLT
     PLSETSLITN SPEDLNLGSE LRAELATADR IDLLCAFVKW YGIRVLEDSL RAARERGVPI
     RVITTTYIGA TDRHALDRLV RDFGATVKVN YETRSTRLHA KAWLFRRRTG FDTAYVGSSN
     LSKAALLDGL EWNVRLSSVA TPAVLNKFEA TFDAYWNDTA FETYDPDLHS ARLDEALAQA
     SGTNASTDLK ISLSGLEVRP YPHQRDMLER LTVERELRGR HRNLLVAATG TGKTVMAALD
     YRSLSRQSEG GRPRLLFVAH RKEILKQSLR TYREVLDDAS FGELLHAGQD PREWNHVFAS
     VQSLNVQRLE QLAPDHFDII VIDEFHHATA ATYRRVIDHF TPKELLGLTA TPERMDGLNV
     QDEFFEGRIA AEMRLWEALE NDLLCPFHYF GMPDGTDLTN LGWQKGSYAD QELGNLYTGN
     HARARIVVKQ IRDKVSHPGA MRALGFCVTK AHAHFMADFF REAGFQAVAL DSDSPAEVRS
     QALSDLRDGK LQVIFSVDLF NEGLDIPDVD TLLLLRPTNS ATVFLQQLGR GLRRTETKPV
     LTVLDFIGQH RAEFRFEEQF RALTNLSRNR LLDHIEHDFP QLPSGCQIIL EGKSKDLVID
     NIRTQLGATV KTLIKEVRAY GTPRLSTYLR ESRREIKELY KSDNSWTTVL RRARLIDEPV
     PSGEAALLKR VHAFLHVDDP ERAEAYLRLL QDDAPPYEDL EPTDQSFARM LFFNLWDNAG
     GFTSFQEGLD SLRDQRVFRD ELRQVISHVI EQADHVPISL SGPLSHVPLK VHSAYNRSEI
     LAALGVARFG GQMPRSFAQG VQWVEELKTD ALLITLEKDE KDFSPTIRYR DYALSPTLFH
     WESQNSTAAN SPTGLRYQQH KARGSHVLLF MRRYKNTDIG KSQPWMLLGP ATYEGHSGSK
     PMAITWRLKH ELPADVWTYS AITGS
//