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Entry: A0A0G3CQC6_9GAMM
LinkDB: A0A0G3CQC6_9GAMM
Original site: A0A0G3CQC6_9GAMM 
ID   A0A0G3CQC6_9GAMM        Unreviewed;       348 AA.
AC   A0A0G3CQC6;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   08-MAY-2019, entry version 21.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   Name=aroG_2 {ECO:0000313|EMBL:SUB82371.1};
GN   ORFNames=NCTC12285_01538 {ECO:0000313|EMBL:SUB82371.1}, QQ39_08515
GN   {ECO:0000313|EMBL:AKJ42123.1};
OS   Pragia fontium.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Budviciaceae; Pragia.
OX   NCBI_TaxID=82985 {ECO:0000313|EMBL:AKJ42123.1, ECO:0000313|Proteomes:UP000068021};
RN   [1] {ECO:0000313|EMBL:AKJ42123.1, ECO:0000313|Proteomes:UP000068021}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=24613 {ECO:0000313|EMBL:AKJ42123.1,
RC   ECO:0000313|Proteomes:UP000068021};
RX   PubMed=26159528;
RA   Snopkova K., Sedlar K., Bosak J., Chaloupkova E., Provaznik I.,
RA   Smajs D.;
RT   "Complete Genome Sequence of Pragia fontium 24613, an Environmental
RT   Bacterium from the Family Enterobacteriaceae.";
RL   Genome Announc. 3:e00740-15(2015).
RN   [2] {ECO:0000313|EMBL:SUB82371.1, ECO:0000313|Proteomes:UP000255526}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC12285 {ECO:0000313|EMBL:SUB82371.1,
RC   ECO:0000313|Proteomes:UP000255526};
RG   Pathogen Informatics;
RA   Doyle S.;
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; CP010423; AKJ42123.1; -; Genomic_DNA.
DR   EMBL; UGTK01000001; SUB82371.1; -; Genomic_DNA.
DR   RefSeq; WP_047780859.1; NZ_UGTK01000001.1.
DR   EnsemblBacteria; AKJ42123; AKJ42123; QQ39_08515.
DR   KEGG; pfq:QQ39_08515; -.
DR   PATRIC; fig|82985.3.peg.1781; -.
DR   KO; K01626; -.
DR   OrthoDB; 853329at2; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000068021; Chromosome.
DR   Proteomes; UP000255526; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000068021,
KW   ECO:0000313|Proteomes:UP000255526};
KW   Reference proteome {ECO:0000313|Proteomes:UP000068021};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:SUB82371.1}.
FT   DOMAIN       39    336       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
FT   COILED       72     92       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   348 AA;  38698 MW;  016573174FECDFF6 CRC64;
     MNKTDELRTA LIDSLVTPER LAQQFPLTAE ISANITQSRK RIEKIIHGED RRLLVIIGPC
     SIHDVDAAMD YAEQLNALRN RYQDRLEIVM RTYFEKPRTV VGWKGMISDP GLDGSYQVNQ
     GLELARDLLL KINKLGLPTA TEFLDMVIGQ YIADLISWGA IGARTTESQI HREMASALSC
     PVGFKNGTDG STKIAIDAIR AARSSHMFLS PDKRGQMSIY RTSGNPYAHI ILRGGKTPNY
     HAADIAVACD NLRQFDLPEH LVVDFSHGNC QKLHRRQLDV CENVCEQIKA GSMAIAGIMA
     ESFLVEGTQK LQPGQPLTYG QSITDSCLSW SDTERMLFNL ATAVDSRF
//
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