ID A0A0G3ELS6_9BURK Unreviewed; 392 AA.
AC A0A0G3ELS6;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:AKJ67890.1};
GN ORFNames=ABW99_06330 {ECO:0000313|EMBL:AKJ67890.1};
OS Pandoraea thiooxydans.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Pandoraea.
OX NCBI_TaxID=445709 {ECO:0000313|EMBL:AKJ67890.1, ECO:0000313|Proteomes:UP000036700};
RN [1] {ECO:0000313|Proteomes:UP000036700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25325 {ECO:0000313|Proteomes:UP000036700};
RA Lim Y.L., Ee R., Yong D., How K.Y., Yin W.F., Chan K.G.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; CP011568; AKJ67890.1; -; Genomic_DNA.
DR RefSeq; WP_047213696.1; NZ_CP014839.1.
DR AlphaFoldDB; A0A0G3ELS6; -.
DR STRING; 445709.ABW99_06330; -.
DR KEGG; ptx:ABW99_06330; -.
DR PATRIC; fig|445709.3.peg.1358; -.
DR OrthoDB; 8951704at2; -.
DR Proteomes; UP000036700; Chromosome.
DR GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43853; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR PANTHER; PTHR43853:SF22; ACETYL-COA ACETYLTRANSFERASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000036700};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:AKJ67890.1}.
FT DOMAIN 5..261
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 270..390
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 90
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 348
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 378
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 392 AA; 41023 MW; B8B983517DDDE18F CRC64;
MPDAVIVSTA RTGLAKSWRG ALNMTHGATL GGHVVQAAIE RARLEPGEVE DVIIGCANPE
GATGFNIARQ IALRAGCPVS TAGMTVNRFC SSGLQTIALA AQRIIAGEGE VYVAGGVESI
SCVQNEMNRH MAQEHFLQET KPALYWPMLQ TAETVASRYG ISRERQDEYG VQSQQRAAAA
AAAGRFDAEI VPLTTRMAVA DKASGRLFTR EVTLAADEGI RADTTYEGVA KIRPAVPGGV
IAAGNASQFS DGAAACVVMS ETLAERRGLQ PLGRFRGFAV AGCEPDEMGI GPVYAVPKLL
ARAGLGVADV GLWELNEAFA VQVLYCRDTL GIPNDRLNVN GGAIAVGHPY GVSGTRLTGH
ALLEGKRRGA RYVVVTMCIG GGQGAAGLFE VL
//
