ID A0A0G3EVM1_9BURK Unreviewed; 318 AA.
AC A0A0G3EVM1;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Glycerate dehydrogenase {ECO:0000313|EMBL:AKJ68806.1};
GN ORFNames=ABW99_11840 {ECO:0000313|EMBL:AKJ68806.1};
OS Pandoraea thiooxydans.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Pandoraea.
OX NCBI_TaxID=445709 {ECO:0000313|EMBL:AKJ68806.1, ECO:0000313|Proteomes:UP000036700};
RN [1] {ECO:0000313|Proteomes:UP000036700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25325 {ECO:0000313|Proteomes:UP000036700};
RA Lim Y.L., Ee R., Yong D., How K.Y., Yin W.F., Chan K.G.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; CP011568; AKJ68806.1; -; Genomic_DNA.
DR RefSeq; WP_047214687.1; NZ_CP014839.1.
DR AlphaFoldDB; A0A0G3EVM1; -.
DR STRING; 445709.ABW99_11840; -.
DR KEGG; ptx:ABW99_11840; -.
DR PATRIC; fig|445709.3.peg.2518; -.
DR OrthoDB; 9805416at2; -.
DR Proteomes; UP000036700; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd12162; 2-Hacid_dh_4; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43761:SF1; 2-HACID_DH DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR43761; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630); 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000036700}.
FT DOMAIN 28..315
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 107..288
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 318 AA; 34189 MW; 038D18CC010A9806 CRC64;
MHKIVFLDRA TLAPQIRLRR PAFAHEWIEY DRTQPHEVAA RLAGATIAIT NKVALREAVL
RDAPGLKLIA VAATGTDCVD KAACRAREVA VSNIRGYAVD TVPEHTFALI LALRRNLVAY
RDDVLAGAWQ RAGQFCFFDH PIHDLRGARL GIVGAGVLGQ RVAELGRAFG MVPLFAAHKG
KSGLGSLYTP WEEMLATSDI ITLHCPLTPH TQGLLALPEF RAMQRRPLII NTARGGLVDE
ADLVTALDEG LVSGAGFDVA AGGEPPPADS PLMRAAHRPN VIVTPHVAWA SDQAQQALAD
QLIANIEAFV GGVRVNEV
//
