ID A0A0G3H5N6_9CORY Unreviewed; 1603 AA.
AC A0A0G3H5N6;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Polyketide synthase family protein {ECO:0000313|EMBL:AKK07123.1};
GN ORFNames=CMUST_14150 {ECO:0000313|EMBL:AKK07123.1};
OS Corynebacterium mustelae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=571915 {ECO:0000313|EMBL:AKK07123.1, ECO:0000313|Proteomes:UP000035199};
RN [1] {ECO:0000313|EMBL:AKK07123.1, ECO:0000313|Proteomes:UP000035199}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45274 {ECO:0000313|EMBL:AKK07123.1,
RC ECO:0000313|Proteomes:UP000035199};
RX PubMed=26358597;
RA Ruckert C., Eimer J., Winkler A., Tauch A.;
RT "Complete Genome Sequence of the Type Strain Corynebacterium mustelae DSM
RT 45274, Isolated from Various Tissues of a Male Ferret with Lethal Sepsis.";
RL Genome Announc. 3:e01012-15(2015).
RN [2] {ECO:0000313|Proteomes:UP000035199}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45274 {ECO:0000313|Proteomes:UP000035199};
RA Ruckert C., Albersmeier A., Winkler A., Tauch A.;
RT "Complete genome sequence of Corynebacterium mustelae DSM 45274, isolated
RT from various tissues of a male ferret with lethal sepsis.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP011542; AKK07123.1; -; Genomic_DNA.
DR RefSeq; WP_047263017.1; NZ_CP011542.1.
DR STRING; 571915.CMUST_14150; -.
DR KEGG; cmv:CMUST_14150; -.
DR PATRIC; fig|571915.4.peg.3037; -.
DR OrthoDB; 9778690at2; -.
DR Proteomes; UP000035199; Chromosome.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.70.250; Malonyl-CoA ACP transacylase, ACP-binding; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR020802; PKS_thioesterase.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR001031; Thioesterase.
DR InterPro; IPR016039; Thiolase-like.
DR NCBIfam; NF040607; mycolic_Pks13; 1.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF00550; PP-binding; 2.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 2.
DR SMART; SM00824; PKS_TE; 1.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000035199};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 14..91
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 113..536
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1138..1212
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1115..1136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1216..1246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1603 AA; 170771 MW; CDF8C576FA13E0AB CRC64;
MDQNDAREQS VVAMTVEQLR SWLRDWVMKT TGLPADEITD DKPMQSFGLS SRDVVILSGE
LENLLNTQLD ATIAYEHPTI AGLAQRIIHG DSAKRAAHTI RKVFSTDQSD PAERDIAIVG
MAARYPGADN VEQMWDMLVA GRDGIGPLPI GRWSEYAADE VMAKRMAELD LTGGYLDDIS
SFDAEFFGLS PLEAVNTDPQ QRIILELTWQ ALENAHIPAN SLKGEAVGVY MGSSNNDYGM
LITADPAEAH PYALTGTASS VIANRVSYVF DFRGPSINVD TACSSSLVSI HHAVQDLRTG
AADVAIAGGV NILAAPFVST AFGELGVFSP TGKIHAFSDD ADGFVRSDGA GVVVLKRVKD
ALADNDEILA VIKGSAVNSD GHSNGLTAPN PEAQVDVLQR AYADAGVDPT QVDYVEAHGT
GTILGDPIEA TAIGAVLGSG REAAKPTLLG SAKTNFGHTE SAAGAAGVIK TVLAMVHDTL
PPSLNYTEPN RYVDFDAEHI EVIEDPREWP EYSGRKLAGV SGFGFGGTNA HVVLSSFDSA
DYGVEPQQQP AQLEGAAVVL PVSGLLPSRR RQAAASVADF VEKLDDAALV PLARSLSGRN
HGRSRAAVIA STTQEAVKRL RMVSDGKLTQ GVAVADSPAM VGPVFVYSGF GSQHRKMVKD
LVAQAPFFKK RLEQLDEIVE FESGWSILDI VADDEQTYDT ETAQVAITAI QIALTDYLAM
LGAKPAAVMG MSMGEIAAAY AAGGLSDADA MQIACHRSRL MGEGEKSLPE DQLGAMAVVE
FSVEQLDQFI AENPDFAGVE PAVYAGPGMS TVGGPREAVV ALVEKLEAEE KFARLLNVKG
AGHTSAVEPL LGELAAEIAG IDPQPLRIPL FSSVDRARVY QPGEVVHDVE YFTRCTRYAV
WFQDATEQAF AAGHTTLVEI SPNPVAMMGM MNTAFFVGKP DAQLLYALKR KVDPAESIPE
LLAKLYVAGA PIDFGALYGS GSIIAAPTVP WKKQRYWTAA RPSSSNSGSV LGHKITLPDG
SIAYGTMADA VPSPIALMEA VIADLAPQAQ LTAVEEHGTL PPSGELTIVA RRNLGGVAIA
VHSVMGDITV AIADGFASTI AADATQPILG SPAVEASAPV PTTEVEDPGL KWDPNSGETV
EQRMRAIVSE AMGYDVEDLP RELPLIDLGL DSLMGMRIKN RIEHDFDIPS LQVQALRDAS
VADAVALVEE LVAGRGSVEQ KPQPAAESPA VDVEKPVGTK PQGVGVAPRD ASERLVFATW
AGITGAAANG VTSELPKLSD EHASAIAARL TERSGAEITA DQVKQAETLE PLANLVREGL
ESEVEGNIRV LRPRPEGSTA PAVFMFHPAG GSSVVYQPLM RRLPADVPVY GVERLEGSLE
DRAAAYLDEI TQYADGYPIV LGGWSFGGVL AYEVAYQLRD RDIDVATIAL LDTVQPAHPA
PDTMEETKNR WQRYSDFAKK TYGLDFPVPF ELLETAGEDA LLAMMAEFLS ETDASEHGLS
AGVLEHQRAS FVDNRILDKI DMHRWADVEV PVMLFRAERM HDGAIELEPA YAEIAYDGGW
SAIVNDLEIV QLAGDHLAVV DEPEIGKVGV ALAKRISQLQ GKL
//
